Penicillin, Quinolones, Tetracyclines

Question 1

Penicillin

Answer 1

Check T100 notes

Extra notes:
- Allergy indicator: Anaphylaxis, hive, immediate rash - AVOID penicillin and other beta lactam ABx
- Minor AEs: Rash after 3 days minor small non itchy - CONTINUE pen.

-IF stopping penicillin more likely start macrolide ALT.

AMOXI key interactions: WAM
Warfarin - Amoxi effects anticoagulant effect
Allopurinol - increases risk of skin rash
Methotrexate - increases risk of toxicity - penicillin’s reduce renal excretion of methotrexate

ALT for penicillin allergy (EXAM Q)
- Clarithromycin
- Erythromycin
- Doxycycline

Question 2

Quinolones

Answer 2

EXAM Q:
Can cause seizures - They reduce seizure threshold.
- NSAIDs + Quinolones can induce seizure

Question 3

Tetracycline’s

Answer 3

T100