PENICILLIN Flashcards
1
Q
Essential to activity
A
Beta-lactam ring
2
Q
_ ring increases with strain and activity
A
Bicyclic
3
Q
Addition of _ group makes penicillin more penicillinase_
A
Bulky group = more penicillinase susceptible
4
Q
_ stereoisomer is essential to activity
A
Cis
5
Q
Presence of electron withdrawing groups (attached to the alpha carbon of the amide side chain)
A
Acid stability