PENICILLIN Flashcards

1
Q

Essential to activity

A

Beta-lactam ring

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2
Q

_ ring increases with strain and activity

A

Bicyclic

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3
Q

Addition of _ group makes penicillin more penicillinase_

A

Bulky group = more penicillinase susceptible

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4
Q

_ stereoisomer is essential to activity

A

Cis

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5
Q

Presence of electron withdrawing groups (attached to the alpha carbon of the amide side chain)

A

Acid stability

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