pemphigus vulgaris Flashcards
1
Q
what is it?
A
an autoimmune disease caused by antibodies directed against desmoglein 3, a cadherin-type epithelial cell adhesion molecule
2
Q
which community is affected?
A
more common in the Ashkenazi Jewish population.
3
Q
which community is affected?
A
more common in the Ashkenazi Jewish population.
4
Q
features
A
mucosal ulceration
skin blistering
acantholysis on biopsy
5
Q
mx
A
steroids 1st line
immunosuppressants
