Pelvic Inflammatory Disease Flashcards
0
Q
PID is a sexually transmitted disease caused by:
A
Neisseria gonnorhea and Chlamydia trachomatis
1
Q
Give some symptoms of PID:
A
Fever (37.8 and up) Moderate bilateral lower abdominal tenderness Foul smelling discharge Severe cervical motion tenderness Bilateral adnexal tenderness
2
Q
If upon laparoscopy, classic violin strings is observed:
A
Fitz Heugh Kurtis
3
Q
Antibiotic given for PID:
A
Quinolone
4
Q
Biochemical mechanism of action of quinolone:
A
Inhibits DNA gyrase/topoisomerase 2 that is responsible for bacterial DNA synthesis
5
Q
Enzyme that assist in formation of superhelices & regulate breaking & rejoining of DNA chain (relaxation of supercoils):
A
DNA topoisomerase
6
Q
MOA of fluoroquinolones in gram positive organisms:
A
Inhibition of topoisomerase IV (interfere w/ separation of replicated chromosomal DNA during cell division)
