Peds UW1 Flashcards

1
Q

kid comes in with obviouse Guillian-barre what is an important test for you to run? why?

A

spirometry to assess respiration = GB pts are at high risk for respiratory failure

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2
Q

Erythema Toxicum Neonatorum(ETN) symptoms

A

asymptomatic, blotchy, erythematous papules and pustles seen in neonates = BENIGN! can change color and always spares palms and sole.

dnt know cause but it will go away so just reassure parents

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3
Q

Chronic Granulomatous Disease

infections with which type of organisms? what will you see on bx?

A

catalase +, numerous organism filled segmented neutrophils

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4
Q

Kids with juvenile idiopathic arthritis obv have arthritis but also have chronic ——. Complications? Tx?

A

Chronic uveitis! Can go blind! Tx w/steroids

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5
Q

what is premature 2nd sex development in girls and bosy?

A

girls <8; boys <9

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6
Q

> 5 yo kid has nocturesis & all other treatment has failure…what do you do?

A

give desmopressin

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7
Q

Neimann-Pick Dz

sx?

A

loss of motor milestones about 2-6m, hypotonia, feeding difficulty, cherry red macula, HEPATOSPLENOMEGLY, AREFLEXIA

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8
Q

bedwetting is normal before the age of….

A

5 = wait to treat untill then.

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9
Q

Tay-Sachs Dz

def? inheritance?

A

AR, B-hemosaminidase A

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10
Q

Neurofibromatosis T2

sx?

A

NF2 mutation = bilateral acoustic neuromas

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11
Q

sx of HUS

A

microangiopathic hemolytic anemia, thrombocytopenia and acute kidney injury

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12
Q

Cervical Lymphadenopathy in children

A

mcc S.aureus = enlarged, tender, erythematous lymph nodes

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13
Q

Gaucher Dz

sx?

A

anemia, thrombocytopenia, HEPATOSPLENOMEGLY, no regression just fatigue and usually appears older kids.

*both this and neimann-pick have hepatosplenomeg but np appears 2-6m w/o blood shit

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14
Q

how can you distinguish central/hypothalamic/pituitary 1 ammenorhea vs peripheral/gonadal

A

check FSH!

  • decrease FSH = central = do MRI
  • increased FSH = peripheral = gonadal prob
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15
Q

Neimann-Pick Dz

def? inheritance?

A

sphingomyelinase, AR

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16
Q
Neurofibromatosis T1(T1 von rec)
mutation? sx?
A

NF1 gene;

  1. cafe-au-lait spots
  2. axillary freckling
  3. monocular eye proptosis & visual changes = OPTIC TRACT GLIOMA
  4. lisch nodules
  5. neurofibromas
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17
Q

Kid has high lead on capillary finger stick. What do you do?

A

Draw venous lead levels bc cap can be false.

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18
Q

Marfans vs Homocystauria

which one has aortic root dilation?

A

marfans

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19
Q

Gaucher Dz

def? inheritance?

A

AR, glucocerebrosidase

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20
Q

common causes of meningitis in kids >11yo

A

N. Men

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21
Q

Sturge-Weber Syndrome

sx?

A

focal or generalized seizures, mental retardation, “Port-wine” stain, IC calcifications

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22
Q

Absence Seizures sx?

A

<20sec, utually 4-10yo, may be accompanied by simple AUTOMATISMS(eye fluttering, lip smacking)

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23
Q

common causes of meningitis in kids 3m-10yo

A

S.pneumo, N. Men

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24
Q

Retinoblastoma

mut? sx?

A

mut Rb; optic nerve retinoblastoma

*associated with osteosarcoma

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25
Q

Tx of tourettes

A

1st line = A2 ag: Clonidine or Guanfacine

2nd line = antipsychotics: Risperidone

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26
Q

Breast Milk Jaundice vs Breasfeeding Failure Jaundice

A
  1. breast milk jaundice: appears in week 1, seen with adequate breastfeeding, normal exam, due to increase conjugate intestinal bilirubin.
  2. breastfeeding failure jaundice: appears in week 1, due to decrease lactation and increase bili, seen w/suboptimal breastfeeding, sx of dehydration = tx by increaseing feeding
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27
Q

Long term consequence of vesicouretral reflux?

A

Renal scarring

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28
Q

Krabbe Dz

def? inheritance?

A

AR galactocerebrosidase

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29
Q

Pellagra

A

Niacin B3 def = diarrhea, dermatitis, dementia, glossitis

30
Q

test for chronic granulomatous disease?

A

check for neutrophils w/dihydrorhodamine 123 tests & nitroblue Tetrazolium test

31
Q

Sx of Lyme dz infection

A

mild pain + joint stiffness that may be on and off, flu like symptoms, fatigue, variable joint pains

32
Q

Chronic Granulomatous Disease

inheritance?

A

XLR

33
Q

Sx of kid with Posterior Urethral Valves

A

potters sequence + hydroureter/nephrosis, usually seen in males

34
Q

What’s neonatal acne?

A

Acne peaks between 2 to 4 weeks occurs due to maternal hormone transmission

35
Q

what vitamin can you give that will decrease mortality in measles?

A

vitamin A

36
Q

tx of SS dz

A

hydroxyurea

37
Q

tx of childhood lead poisoning

moderate vs severe

A
  • moderate(45-69): Meso-2,3-dimercaptiosuccinic acid(DMSA)

- severe(>70): DMSA + Calcium disodium edetate(EDTA)

38
Q

Describe Dermatatitis Herpetiformis. What its associated with?

A

“red spots on arms and legs filled with clear fluid that later crusts over”

39
Q

GI “target sign” is associated with….

A

intusseption

40
Q

causes of baterial rhinosinusitis

A

Strep. Pneumo > H. Influenza > Moraxella Cat

41
Q

What’s a herald patch?

Tx?

A

Pityriasis Rosea ! Associated w/HSV 6/7 but not sure which. Lasts 2-12 weeks tx w/topics steroids

42
Q

What is adequate breastfeeding?

A

breastfeeding 8-12 times a day every 2-3 hrs for about 10-20 min per breast during the 1st month

43
Q

Bow legs is normal till…

A

2y

44
Q

Friedreich Ataxia

sx?

A

ataxia, dysarthria, degradation of spinocerebellar tracts, hypertrophic cardiomyopathy, diabetes, skeletal deformities(kyphosis, scoliosis)

45
Q

Friedreich Ataxia

mutation? inheritance?

A

AR mut in fraxtin = GAA triplet

46
Q

HUS causes hematuria by….

A

vascular dmg causing microthrombi = mechanical dmg

47
Q

Henoch-Scholein Purpura sx

A

low grade fever, cough, nonblanching rash on butt and legs, arthralgias, abdominal pain, intussecption, kidney shit

48
Q

Kawasaki Disease diagnosis criteria

what are they at increased risk for?

A

fever >5d +4 or more:

  1. conjunctivitis
  2. mucositis(strawberry tongue)
  3. cervical lymphadenopathy
  4. rash
  5. erythema & edema of the hands and feet

*increased riks of coronary artery aneuryms

49
Q

Marfans vs Homocystauria

which one has mental retardation?

A

homocystauria

50
Q

Marfans vs Homocystauria

which one has fair complection?

A

homocystauria

51
Q

Scarlet Fever sx + tx?

A

*seen w/untreated strep shit

fever, chills, sore throat, strawberry tongue, rash(sunburn w/goosebumps or sandpaper or rough texture)

52
Q

common causes of meningitis in kids <3m

A

GBS, Ecoli, Listeria, HSV

53
Q

Kid with toothache has been using numbing cream to treat. now presents w/cyanosis, pulse ox 85%. dx? why? tx?

A

methemoglobinemia, caused by oxidizing agents = dapson, nitrates, topical anesthetics(benzocaine & lidocaine)

  • will see normal PaO2, saturation gap, normal arterial partial pressure
    tx: methylene blue
54
Q

McCune-Albright Syndrome

A

de novo mut in G-protein cAMP(GNAS)

Triad: precocious puberty, cafe-au-lait spots, fibrous dysplasia of bones

+ HYPERENDOCRINE due to increased cAMP activity = elevated cortisol = cushing symptoms

55
Q

Riboflavin B2 deficiency

A

Chelioliss, Glossitis, seborrhetic dermatitis, pharyngitis,

56
Q

Fanconi anemia

sx?

A

XLR aplastic anemia with progressive bone marrow failure, short stature, hypergonadism, hypo pigmentation, low set ears, deafness, abnormal thumbs, microcephaly, cafe au lair spots

57
Q

Tay-Sachs Dz

sx?

A

loss of motor milestones around 2-6m, hypotonia, feeding difficulties, cherry red macula, HYPERFLEXIA

58
Q

MCC of sepsis in SS dz

What can you do for them?

A

S. Pneumo = pplx with PCN till the age of 5

59
Q

Pertussus ppx for baby

A

erythromycin

60
Q

RDW in iron deficiency vs thalassemia

A

RDW is increased in iron but normal in thalassemia

61
Q

what is the most common congenital heart defect in kids with DS?

A

complete AV septal defect

62
Q

RF for RDS in newborns?

A

Prematurity, male sex, perinatal asphyxia, maternal DM, C-section w/o labor

63
Q

what effect doesn PROM have on RDS?

A

decreases RDS due to increase stress = cort = help lungs mature

64
Q

Trendelenburg Gait

A

hip drop due to dmg to superior gluteal N = weak gluteus muscles

65
Q

CF infertility in men. why?

A

congential absence of vas def

66
Q

Premature baby give vaccinations according to —– age. What the exception?

A

chronological; exc: HepB! baby must be >2kg for this vaccination

67
Q

Trachoma

A

chlamydia infection in the eye that can spread in unsanitary condition like a refugee camp.

  1. conjunctival injection
  2. tarsal inflammation(eye lid)
  3. pale follicles(bumps under eye lid)
  4. often seen w/rhinorhea, pharyngitis

tx: azithromycin

68
Q

Which nephrotic syndrome is most associated with…

  1. HBV?
  2. HIV?
  3. A1AT?
A
  1. HBV = membranous
  2. HIV = FSGS
  3. A1AT = membranoproliferative
69
Q

SS trait causes spontaneously resolving hematuria due to….

A

microthrombi causing renal papillary necrosis

70
Q

Werdnig Hoffman dz vs Botulism

A

WH: anterior horn degen; upper ext > lower, lacks eye shit

Bot: hx of ingestion; Ptosis, sluggish pupillary light reflex

BOT SPORES: no hx of ingestion, kid will be breast fed; Ptosis, sluggish pupillary light reflex