Pedigrees Flashcards
Pedigree analysis
A diagram of a family’s history with a given trait, used with humans
Examples of single gene traits in humans
Sickle cell disease, albinism, Huntington Disease
Albinism
Missing enzyme for melanin, recessive, epistatic
Sickle cell disease
Mutant allele for hemoglobin, recessive, malaria resistance
Dominance is condition dependent
Huntington disease
Dominant trait, late onset, nerve cell degeneration, lethal
Karyotypes
Image of all chromosomes, allows visibility of chromosome abnormalities
Autosomal trait
from a gene not on a sex chromosome
Sex-linked trait
From a gene on the X or Y chromosome
Under what conditions is sickle cell disease dominant?
Malaria resistance is dominant
Under what conditions is sickle cell disease recessive?
At sea level
Under what conditions is sickle cell disease incomplete dominant?
The cell concentration at high altitudes
Under what conditions is sickle cell disease codominant?
At high altitudes