Pedigrees Flashcards

1
Q

Pedigree analysis

A

A diagram of a family’s history with a given trait, used with humans

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2
Q

Examples of single gene traits in humans

A

Sickle cell disease, albinism, Huntington Disease

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3
Q

Albinism

A

Missing enzyme for melanin, recessive, epistatic

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4
Q

Sickle cell disease

A

Mutant allele for hemoglobin, recessive, malaria resistance
Dominance is condition dependent

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5
Q

Huntington disease

A

Dominant trait, late onset, nerve cell degeneration, lethal

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6
Q

Karyotypes

A

Image of all chromosomes, allows visibility of chromosome abnormalities

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7
Q

Autosomal trait

A

from a gene not on a sex chromosome

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8
Q

Sex-linked trait

A

From a gene on the X or Y chromosome

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9
Q

Under what conditions is sickle cell disease dominant?

A

Malaria resistance is dominant

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10
Q

Under what conditions is sickle cell disease recessive?

A

At sea level

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11
Q

Under what conditions is sickle cell disease incomplete dominant?

A

The cell concentration at high altitudes

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12
Q

Under what conditions is sickle cell disease codominant?

A

At high altitudes

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