Pedigree rules Flashcards
autosomal recessive
-both male and females
-skips generations
-affected offspring’s usually born to unaffected parents
-1/4 of offspring will be affected when both parents are heterozygous
-appears more frequently when parents are related
autosomal dominant trait
-appear equally in males and females
-does not skip generations
-unaffected people do not transmit the trait
-affected people have at least one affected parent
-when one parent is affected (heterozygous) and the other parent is unaffected, approximately half of the offspring will be affected
x linked recessive
-appear more often in males
-affected male cannot pass trait to son but can pass allele to daughter who is unaffected but can pass it to her sons who will be affected
-Classic hemophilia is inherited as an X-linked recessive
-trait skips generations
-all daughters of affect fathers are carriers, never passed from father to son
x linked dominant
-do not skip generations
-affects both males and females
-affected males pass trait to all their daughters, none of their sons
-affected females (if heterozygous) pass the trait on to about half of their sons and half of their daughters
-often more females than males
y linked
-appear only in males
-all male offspring’s are affected
-passed father to all son