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Pharmacology > Pediatrics Pharmacology > Flashcards

Pediatrics Pharmacology Flashcards

1
Q

Glucuronide formation reaches adult values at

A

Age 3-4

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2
Q

T/F. Neonates have slower clearance and prolonged elemination half-lives

A

True

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3
Q

T/F. If mom is receiving drugs, chances are neonates will not be able to metabolize durgs faste

A

False

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4
Q

T/F. Toddles have the highest metabolism rate

A

True

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5
Q

Mother has lack of milk, infant becomes dehydrated causing hyperbilirubinemia

A

Breastfeeding jaundice

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6
Q

Breastmilk jaundice

A

Mother’s breastmilk has high glucuronidase

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7
Q

GFR and renal plasma flor have increased 50% from day 1

A

1 wk old

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8
Q

GFR 50-60%

A

3 wk old

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9
Q

GFR reaches adult value

A

6-12 mos old

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10
Q

Exceeds drug metabolism

A

Tiddlerhoid

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11
Q

30-40% adult GFR

A

Newborn

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12
Q

Unique factors influencing drug absorption

A

Blood flow

GI function

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13
Q

GI secretion og neonate starts

A

Soon after birth

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14
Q

GI secretion of premies is highes on

A

4th day of life

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15
Q

Gastric emptying is prolonged up to

A

6-8 hrs in the first day of life

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16
Q

Oral abs of these drugs is increased

A

Ampicillin, penicillin

17
Q

Oral abs of these drugs is decreased

A

Acetaminophen
Phenobarbital
Phenytoin

18
Q

Oral abs of these drugs is normal

A

Diazepam
Digoxin
Sulfonamide

19
Q

Who has higher body water, neonate or adult

A

Neonate > adult

20
Q

Who has higher body water preterm infant or neonate

A

Preterm > neonate

21
Q

Most neonates experience diuresis eithin

A

24-48 hrs

22
Q

Who has higher total body preterm or neonate

A

Premie

23
Q

This drug displaces bilirubin

A

Sulfonamide

24
Q

This drug is displaced by bilirubin

A

Phenytoin

25
Q

Glucuronide formation reaches adult values at age

A

3-4

Pharmacology (3 decks)

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