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Pharmacology > Developmental Pharmacology > Flashcards

Developmental Pharmacology Flashcards

1
Q

Drug used for caesarean sections

A

Thiopental

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2
Q

An ionized but highly lipophilic drug

A

Salicylate

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3
Q

Anti-coagulant given to pregnant mothers

A

Heparin

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4
Q

Moleculle that can cross the placenta even if they are very large

A

Maternal antibody

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5
Q

Some drugs with greater affinity for maternal rathen than fetal

A

Sulfonamides
Barbiturates
Phenytoin
Local anesthetics

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6
Q

Interferes with normal maturation & function

A

Hadegen

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7
Q

Agent that alters growth

A

Trophogen

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8
Q

Examples of basoc drugs

A

Lidocaine
Beta blocker
Tricyclic anti-depressanta

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9
Q

Immediate fetal drug thay induces limb deformities

A

Thalidomide

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10
Q

Immediate fetal drug that can cause craniofacial, cardiac, CNS defects

A

Retinoic acid

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11
Q

Produces phocomelia

A

Thalidomide

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12
Q

Hydrocephalus

A

Valproate

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13
Q

E: cleft lip/palate

A

Phenytoin

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14
Q

E: masculinization in female fetus

A

Androgen, progestin

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15
Q

E:craniofacial abnormalities

A

Ethanol

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16
Q

DELAYED E: affects bone growth

A

Tetracycline

17
Q

Delayed E: non-ateroidal estrogen used for vaginitia and some menopausal syndromes

A

Diethylstilbestrol

18
Q

DE: Teeth staining

A

Tetracycline

19
Q

DE: Adenocarcinoma of the vagina and genital malformations

A

Diethystilbestrol

20
Q

DE: learning disabilities

A

Ethanol, cocaine

21
Q

Categpry B drugs

A

Amoxicillin, cefuroxime, loratadine

22
Q

Category C drugs

A

Acyclovir, fluconazole, metoprolol

23
Q

Category D

A

Benzodiazepine

24
Q

Category X

A

Warfarin, diethylstilbestrol, methotrexate

25
Q

Lactating mom E: teeth staining

A

Tetracyclin

26
Q

Lactating mom E: kernicterus

A

Sulfonamide

27
Q

Lactating mom E: gray baby syndrome

A

Chloramphenicol

28
Q

Lactating mom E: pyridoxine deficiency

A

Isoniazid

29
Q

Lactating mom E: lethargy, sedation, poor suck reflex

A

Barbiturates

30
Q

Lactating mom E: sedation

A

Chloal hydrate

31
Q

Lactating mom E: sedation, drug accumulation

A

Diazepam

32
Q

Lactating mom E: narcotic independence

A

Opioids

33
Q

Lactating mom E: fetal alcohol syndrome

A

Alcohol

34
Q

Lactating mom E: breast milk conc = maternal serum conc

A

Lithium

35
Q

Lactating mom E: low birth wt, mental retardation

A

Nicotine

36
Q

Lactating mom E: thyroid suppression, thyroid cancer

A

Eadioactive substances

Pharmacology (3 decks)

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