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PHARM 303 > Pediatrics Enzymes > Flashcards

Pediatrics Enzymes Flashcards

1
Q

CYP1A2

A

No activity in fetus
Reduced activity in neonate and infant
Reaches adult level at childhood

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2
Q

CYP2C9

A

Reduced Activity in Fetus, Neonate, Infant
Greater than adult levels in childhood
Reaches adult levels at adolescent

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3
Q

CYP2C19

A

Reduced Activity in Fetus, Neonate, Infant
Greater than adult levels in childhood
- Occurs sooner
Reaches adult levels at adolescent

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4
Q

CYP2D6

A

Reaches adult level at infant

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5
Q

CYP2E1

A

Reaches adult level at child

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6
Q

CYP3A4

A

Reaches adult level at infant
Greater than adult level at child
Reaches adult level at adolescent

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7
Q

UDP

A

Reaches adult level at child

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8
Q

NAT2

A

Reaches adult level at child

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9
Q

Methyltransferase

A

Reaches adult level at infant

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10
Q

Sulfotransferase

A

Reaches adult level at adolescent
(Certain substrates are greater than adults at infant and child)

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PHARM 303 (10 decks)

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