Pediatrics Flashcards
Treatment for tinea capitus
- 1st Line: Oral griseofulvin
- topical therapy of 2.5% selenium sulfide or ketoconazole shampoo twice weekly suppresses viable spores
Tinea pedis
- mc org
Trichophyton rubrum
Tinea pedis
- treatment
Topical antifungals
Tinea corporis
- mc org
Trichophyton rubrum
Tinea corporis
- treatment
- Topical azole antifungals (1% clotrimazole, 2% ketoconazole)
- 1% terbinafine cream applied twice daily for 2–4 weeks
Tinea versicolor
- org
Malassezia furfur
Tinea versicolor
- treatment
selenium sulfide 2.5% applied to affected skin for 10 minutes.
Do hives blanch?
Yes
Darier’s Sign
localized urticaria appearing where the skin is rubbed
Darier’s Sign
localized urticaria appearing where the skin is rubbed
Epinephrine treatment of anaphylaxis
- Dose adults
- Dose peds
- IM dilution
- IV dilution
- Adults 0.3–0.5 mg
- Peds 0.01 mg/kg SC/IV
- IM is 1:1,000 dilution
- IV is 1:10,000
Name for genital warts
Condyloma acuminatum
Name for genital warts
Condyloma acuminatum
Acute vs. chronic otitis media
- acute < 3 weeks
- chronic > 3 months
Definition of recurrent otitis media
3 episodes in 6 months
or
4 episodes in 12 months
with clearing between episodes
Chronic OM
- Clear serous fluid in the middle ear without signs or symptoms of ear infection.
- May have hearing loss, may be asymptomatic, does not require antibiotics.
- pseudomonas, s. aureus
Acute otitis media
- treatment
- First line: Amoxicillin x 10-14 days
- Cefixime in children
- Augmentin is 2nd line
- If PCN allergic give Azithromycin, Erythromycin or Bactrim
MCC epiglottitis
H. influenzae type B (Hib)
MCC epiglottitis
H. influenzae type B (Hib)
Epiglottitis
- xray sign
thumbprint sign
Epiglottitis
- treatment
- Secure airway: anesthesiology and prepare to establish airway, transfer to OR to perform exam, tracheostomy if necessary to maintain airway
- Admit for observation, humidified O2, IV antibiotics (ceftriaxone + clindamycin), and IV corticosteroids
Epistaxis: anterior bleed
- MC location
Kiesselbach’s Plexus
Epistaxis: posterior bleed
- MC location
- Woodruff’s Plexus: sphenopalatine artery
Epistaxis: anterior bleed
- treatment
- Direct pressure at least 10-15 minutes, seated leaning forward
- Short-acting topical decongestants: oxymetazoline/Afrin, phenylephrine, cocaine
- Anterior nasal packing + antibiotics
Epistaxis: posterior bleed
- treatment
- Posterior balloon
- Must be admitted to the hospital and prompt consultation with an otolaryngologist is indicated
Recurrent epistaxis
- workup
Must rule out hypertension or hypercoagulable disorder
Antiviral for influenza
zanamivir and oseltamivir
Treatment for pinworms
mebendazole, albendazole, pyrantel
- single dose, repeat 2-4 weeks
- hand washing
- wash bedsheets
Erythema infectiosum
- causative org
parvovirus B19
hand foot and mouth
- causative org
coxsackie virus
Roseola
- causative org
HHV 6 or 7
Roseola
- clinical presentation
- fever, resolves before rash appears
- pink, macular rash, blanchable
Pneumonia MCC
<1
<2
young adults/college
- RSV
- parainfluenza virus
- mycoplasma pneumoniae, chlamydia pneumoniae
What respiratory condition should bulbous myringitis make you think of?
mycoplasma pneumoniae pnuemonia
outpatient CAP treatment
- macrolide (clarithromycin or azithromycin)
- doxycycline
bronchiolitis
- management
- supportive: ensure oxygenation and hydration
- RSV: consider hospitalization and admin of ribavirin, esp if high risk pt (premie, underlying conditions, severely ill)
- nebulizer albuterol, IV fluids, antipyretics, chest physiotherapy, humidified O2
croup
- aka
laryngotracheobronchitis
croup
- MCC causative orgs
- parainfluenza types 1 and 2
- RSV
- adenovirus
- influenza
- rhinovirus
croup
- clinical findings
- harsh, barking, seal-like cough
- inspiratory stridor
- hoarseness
- aphonia
- low-grade fever
- rhinorrhea
croup
- treatment
Mild: hydration, cool humidified air, dexamethasone
Moderate: IM/PO dexamethasone, supportive, +/- nebulized epinephrine
Severe: dexamethasone, nebulized epinephrine, hospitalize (O2 < 92%)
how should asthma spirometry respond to albulterol
FEV1 or FVC increase > 12%
Asthma
- CXR
- ABG
- hyperinflation
- hypocarbia: have increased respiratory rate. If normal or high, may be sign of impending respiratory failure
Intermittent Asthma
- daytime sx / SABA use
- nighttime sx
- interference with activities
- FEV1
- ≤ 2 days/week
- ≤ 2 times a month
- no interference
- FEV1 >80% predicted
Mild persistent asthma
- daytime sx / SABA use
- nighttime sx
- interference with activities
- FEV1
- > 2 days/week, not daily
- 3-4 times a month
- minor
- FEV1 >80% predicted
moderate persistent asthma
- daytime sx / SABA use
- nighttime sx
- interference with activities
- FEV1
- Daily
- > once a week, not nightly
- Some interference
- FEV1 60-80% predicted
severe persistent asthma
- daytime sx / SABA use
- nighttime sx
- interference with activities
- FEV1
- multiple times daily
- daily
- extremely limited
- FEV1 < 60% predicted
Asthma therapy steps
Step 1: SABA
*steps 2-6 SABA plus…
Step 2: Low dose ICS
Step 3: medium dose ICS OR low dose ICS + LABA/montelukast/theophylline
Step 4: medium dose ICS + LABA/montelukast/theophylline
Step 5: high dose ICS + LABA +/- omelizumab
Step 6: high dose ICS + LABA + oral steroid =/- omelizumab
Cystic fibrosis
- genetics
- overview
- autosomal recessive
- abnl production of mucus by almost all exocrine glands = obstruction
Cystic fibrosis
- clinical
- chronic lung dz, bronchiectasis, pancreatitis, infertility
- sx: cough, sputum, dec exercise tolerance, sinus pain, purulent nasal dc, steatorrhea, diarrhea, abd pain
- signs: clubbing of fingers, anteroposterior chest diameter inc, apical crackles
Cystic fibrosis
- dx studies
- ABG: hypoxemia and possible compensated respiratory acidosis
- PFT: mixed obstructive and restrictive
- CXR: hyperinflation, peribronchial cuffing, mucous plugging, bronchiectasis, inc insterstitial markings, etc.
- GS: sweat chloride test (>60 mEq/L) on two diff days, then DNA testing for definitive evidence
Hyaline membrane disease
- aka
respiratory distress syndrome, RDS
hyaline membrane disease/RDS
- general
- MC cause resp distress in preterm infant
- deficiency of surfactant
hyaline membrane disease/RDS
- dx
- CXR: air bronchograms, diffuse bilateral atelectasis causing a ground-glass appearance, doming of the diaphragm
hyaline membrane disease/RDS
- management
- synchronized intermittent ventilation
- exogenous surfactants
Cyanotic heart defect
right-to-left shunt (skipping the lungs)
Four cyanotic heart defects
- Tetralogy of Fallot
- Pulmonary atresia
- Hypoplastic left heart
- Transposition of the great arteries
Tetralogy of fallot
- define anomoly
- ventricular septal defect
- aortic origination over defect (aortic override)
- right ventricular outflow obstruction
- right ventricular hypertrophy
Tetralogy of fallot
- murmur
crescendo-decrescendo
holosytolic
LSB
radiates to back
Tetralogy of fallot
- physical findings
cyanosis
clubbing
increased RV impulse at LLSB
Loud S2
Tetralogy of fallot
- clinical information
- polycythemia usually present
- tet spells: extreme cyanosis, hyperpnea, agitation (medical emergency)
noncyanotic congenital heart anomalies (5)
- atrial septal defect
- ventricular septal defect
- atrioventricular septal defect
- patient ductus arteriosus
- coarctation of the aorta
Atrial septal defect
- MC subtype
osmium secundum
Atrial septal defect
- murmur
- systolic ejection murmur at 2nd LICS
- early to middle systolic rumble
Atrial septal defect
- physical findings
- failure to thrive
- fatigue
- RV heave
- wide fixed split S2
Ventricular septal defect
- three types
- perimembranous (MC)
- muscular
- outlet openings btwn ventricles
Ventricular septal defect
- murmur
systolic murmur at LLSB
Ventricular septal defect
- physical findings
asx to signs of CHF
Patent Ductus Arteriosus
- describe
- failed or delayed closure of ductus arteriosus between pulmonary artery and aorta - allows placental gas exchange during fetal state, bypasses the lungs
- sx treatment generally not indicated
Patent Ductus Arteriosus
- treatment
IV indomethacin (reduction of prostaglandins)
Patent Ductus Arteriosus
- murmur
continuous (machine like) murmur
Patent Ductus Arteriosus
- physical findings
- wide pulse pressure
- hyper dynamic apical pulse
Coarctation of the aorta
- describe
narrowed proximal thoracic aorta
Coarctation of the aorta
- murmur
- systolic, LUSB/left intrascapular area
- may be continuous
Coarctation of the aorta
- physical findings
- infants: CHF
- older: systolic hypertension or underdeveloped lower extremities
- difference between UE and LE blood pressure is pathognomonic
Treatment for cyanotic defects prior to surgical correction
- if PDA: prostaglandins to maintain
Hypertrophic cardiomyopathy
- presentation
- dyspnea and angina
- syncope and arrhythmias common
- asx to sudden death
Hypertrophic cardiomyopathy
- dx
- EKG: nonspecific ST- T-wave changes, exaggerated septal Q wave, LVH
- Echo: key to dx. LVH, asymmetric septal hypertrophy, small LV, diastolic dysfunction
Hypertrophic cardiomyopathy
- management
- BB or CCB, disopyramide
- sx or nonsx ablation of hypertrophic septum
- dual-chamber pacing, implantable defibrillators, mitral valve replacement
Rheumatic fever
- describe
2-3 weeks following beta-hemolytic strep pharyngitis
- ages 5-15 MC
- self-limited to progressive valve deformity
Rheumatic fever
- valves affected
- MC: mitral valve
- also aortic valve
Rheumatic fever
- Jones criteria
2 major
or
1 major + 2 minor
Rheumatic fever
- Major jones criteria
- carditis
- erythema marginatum
- subcutaneous nodules
- chorea
- polyarthritis
Rheumatic fever
- minor jones criteria
- fever
- polyarthralgias
- reversible prolonged PR interval
- rapid ESR
- CRP
Rheumatic fever
- management
- bed rest
- IM penicillin (erythromycin if PCN allergic)
- antipyretics and steroids to reduce joint sx
Rheumatic fever
- prevention
early tx of strep pharyngitis
Kawasaki dz
- aka
- etiology
- aka mucocutaneous lymph node syndrome
- etiology unknown, suspect virus
Kawasaki dz
- presentation
- fever > 5 D
AND 1+: - conjunctivitis
- lip crack/fissure, strawberry tongue, inflammation oral mucosa
- cervical lymphadenopathy
- polymorphous exanthem
- red/swelling of hands and feet, subsequent desquamation
Kawasaki dz
- cardiac involvment
- worrisome
- myocarditis, pericarditis, valvular heart disease, coronary arteritis, aneurysms all possible
Kawasaki dz
- Testing for all pts
- 2D echo or angiography to r/o heart involvement
Kawasaki dz
- treatment
- IV immunoglobulin, high dose ASA
- early treatment -> lower chance cardiac involvement
- cardiac involvement: long term ASA and annual f/u
Cause of intussusception
- child
- adult
- follows URI
- neoplasm
(proximal goes into distal portion)
Intussusception
- dx
barium or air enema
- diagnostic and therapeutic
- if not, then surgery
Vitamin A deficiency
- function
- s/sx
- vision, epithelial cell maturity, infection resistance, antioxidant
- night blindness, dry skin, squamous metaplasia, bitot’s spots
Vitamin C deficiency
- function
- s/sx
- collagen synthesis, hormone function, nt synthesis
- scurvy: hyperkeratosis, hemorrhage, hematologic (3 Hs)
Vitamin D deficiency
- function
- s/sx
- calcium regulation, cell differentiation
- rickets, osteomalacia
Niacin deficiency
- function
- s/sx
- energy, fat metabolism
- Pellagra: diarrhea, dementia, dermatitis (3 Ds)
eosinophilic esophagitis
- associated with what
- clinical
- atopic disease
- dysphagia, +- reflux or feeding difficulties in children
eosinophilic esophagitis
- dx
- management
- endoscopy: normal +- multiple corrugated rings +- white exudate
- remove foods that incite allergic response, inhaled topical corticosteroids
Crigler-Najjar syndrome
- Type 1
no UGT activity = no conversion of indirect to direct bilirubin
- neonatal jaundice with severe progression in the 2nd week, leads to kernicterus
- normal LFTs, indirect bilirubin 20-50 mg/dL
- Tx: phototherapy, plasmapheresis, liver transplant
Duodenal atresia
- clinical
- XR findings
- polyhydramnios in pregnancy, inc risk in Downs
- intestinal obstruction shortly after birth, abd distention, bilious vomiting
- double-bubble sign
Duodenal atresia
- management
- decompression fo GI tract
- electrolyte and fluid replacement
- duodenoduodenostomy: repair or anastomosis
what is the only childhood exanthem that starts on the trunk?
roseola
when do annual blood pressure readings start (age)
3 yo
when should intermittent alternating strabismus stop (age)?
6 months
when does the rooting reflex stop?
2-3 months
by what age should posterior fontanelle close?
2 months (usually closed at birth)
What drug is used to treat Lyme disease in kid <8 yo
amoxicillin
What level of bilirubin is suspicious for kernicterus?
20-25 mg/dL
** encephalopathy
Hyperbilirubinemia
< 24 hours old
>24 hours old
< 24 is more worriesome for non-physiologic causes (ABO, Rh isoimmunization, etc.)
What maternal blood types can lead to hyperbilirubinemia in the infant?
- O
- Rh neg
Down syndrome
- dx sx
- hypotonia
- poor Moro reflex
- hypermobility of joints
- flattened facies and occiput
- excess posterior neck skin
- anomalous auricles
- upward-slanting palpebral fissures
- pelvic dysplasia
- dysplasia of middle phalanx of 5th finger
- Simian crease
Down syndrome
- common congenital defect
ASD
what should always be considered in neonate presenting with fever
herpes simplex infection
herpes simplex meningitis neuro signs
seizures
lethargy
poor feedings
Test of choice to confirm CNS herpes simplex
PCR of cerebrospinal fluid
Four signs of neonatal herpes simplex infection
- keratoconjunctivitis
- vesicular skin rash
- seizure meningitis
- sepsis
Duodenal atresia
- s/sx
- xray findings
- management
- associated with what
- bilious vomiting w/o abd distention within first days of life
- double bubble sign on XR
- NG or OG decompression, IVF until surgery
- Down’s syndrome
What RA finding is rarely found in juvenile idiopathic arthritis
rheumatoid factors
What are the three types of juvenile idiopathic arthritis?
- systemic juvenile idiopathic arthritis
- Oligoarticular juvenile arthritis
- Polyarticular juvenile arthritis
Major clinical manifestation of juvenile idiopathic arthritis
persistent joint swelling that may lead to deformity
What is the age range for febrile seizures
6 months to 5 years
Definition of simple febrile seizure
- tonic clonic
- less <15 min
- only once w/in a febrile episode
Simple febrile seizure RF
- elevated fever
- viral infection
- fam hx
- recent immunization
Treatment for recurrent febrile seizures
- if >5 min, diazepam gel or suppository (one dose)
Presentation of CF
- chronic sinopulmonary disease: persistent infection with CF pathogens, chronic cough/sputum, chest xr abnl, airway obstruction, nasal polyps, digital clubbing
- GI and nutritional abnl: meconium ileum, distal GI obstruction, rectal prolapse, pancreatic insufficiency, DM, chronic hepatic dz, FTT, etc.
- salt loss syndromes
- male urogenital abnl
CF
- management
- meds to clear resp secretions (DNase and inhaled hypertonic saline)
- chest physiotherapy
- anti-inflammatories
- nutritional optimization
- exercise as tolerated
- *anti-pseudomonal abx when indicated
what two sugars form lactose
glucose
galactose
Prolonged QT syndrome
- common presentation
syncope
presyncope, torsades de pointes, sudden cardiac death
Prolonged QT syndrome
- QT interval
> 440 milliseconds
Prolonged QT syndrome
- 1st line treatment
beta blockers - blunt paradoxical effects of catecholamine on QT interval
concerning sign for pathologic murmur
widely split and fixed S2
mastoiditis
- s/sx
- anteverted ear
- pain with palp of post auricular area
Mastoiditis
- dx
CT - coalescence of air cells, subperiosteal abscess
Mastoiditis
- management
- sx
- prolonged abx (initial vanc and ceftriaxone)
- possible tympanostomy tubes
Effects of fetal coarctation of the aorta in utero
blood flow through PDA bypasses the coarctation, resulting in hemodynamic stability
what electrolyte disorder is commonly seen in hyperparathyroidism
hypercalcemia
What two meds are known to exacerbate hypercalcemia
- thiazide diuretics
- lithium
Lead testing
- screening
- definitive test
- capillary blood for screening: easier to get but easily contaminated yielding false positives
- venous blood: confirms dx and guides management based on levels
common lead poisoning sx
- HA
- joint pain
- constipation
Lead poisoning
- management
- education
- remove lead
- oral succimer
- IV EDTA
- > 45 mcg/dL = chelation
CF dx
- test of choice
- another test
- Sweat chloride test
- Fecal elastase - elevated: indicates malfunction of exocrine pancreas
Perforated TM
- management
- min hearing loss, no vestibular sx
- ofloxacin drops
- keep ear dr
- f/u primary care in 4 weeks: audiometry to assess hearing loss and healing of TM
what type of ear drops are ototoxic
gentamicin - only use if positive TM is not perforated
f/u for breech baby with unremarkable exam and no family hx of developmental hip dysplasia
- US of hips at 4-6 weeks
developmental hip dysplasia
- RF
- female
- breech> 34 weeks
- fam history
- tight lower extremity swaddling
developmental hip dysplasia
- testing
- Barlow and Ortolani: subluxation = hip laxity or mild instability
- Galeazzi: unequal height of legs or asymmetrical skin folds
developmental hip dysplasia
- tx for <6 mo
Pavlik harness
Hereditary spherocytosis
- RBCs
biconcave shape
Howell-jolly bodies
Hereditary spherocytosis
- heredity
autosomal dominant
Hereditary spherocytosis
- PE findings
- splenomegaly
- jaundice
- scleral icterus
- microcytic/normocytic anemia
- reticulocytosis
- ** increased MCHC
- Coombs negative
What is cryptorchidism associated with?
low birth weight
prematurity
When do undescended testes usually descend
- by three or four months
- ## after 6 months, rare to descend further
Management of undescended testes after four months
surgical orchiopex
Complications associated with cryptorchidism
testicular torsion
infertility
malignancy
Croup
- Clinical
- URI sx
- barking, seal cough
- stridor
- sx worse at night
- hypoxia UNCOMMON
Croup
- management
- cool, humidified air
- racemic epinephrine
- corticosteroids (dexamethasone)
Acute otitis media
- abx algorithm
1st line: amoxicillin
2nd line: amox-clavulanate (Augmentin)
3rd line: Cefixime, Cefaclor
4th line: Ceftriaxone
Acute otitis media + conjunctivitis
- mc org
H. influenza
Acute otitis media + conjunctivitis
- abx
Augmentin
Non-accidental Trauma
- suspicious fracture (6)
- metaphysical fracture (pathognomonic)
- Rib fx
- skull fx
- scapular fx
- sternal fx
- transverse long bone fx
Injuries suggestive of non-accidental trauma
- bruises and fractures in various stages of healing
- retinal hemorrhage
- cigarette burns
- glove-and-stocking pattern burns
Comedonal acne
- treatment
- topical retinoid
- azelaic acid/salicylic acid
Mild papulopustular and mixed acne
- treatment
- topical antimicrobial (benzoyl peroxide/abx) and topical retinoid
OR - benzoyl peroxide and topical abx