Pediatrics 2 Flashcards
kid with drooling fever odynophagia dysphagia muffled voice and trismus what can cause that(3)
infection of larynx
Pharynx
or
deep neck space
clue for retropharyngeal abcess in the setting of drooling fever odynophagia dysphagia muffled voice and trismus(2)
inability to extend the neck
widened prevertebral space in lateral xray
complication of retropharyngeal abcess(4)
airway compromise
bactriemia
carotid artery rupture
jugular venous thrombosis
cause of retropharyngeal abcess
direct spread infection from paharyngitis
tonsilitis
otitis media
or sinusitis
bugs involved in retropharyngeal abcess
polymicrobial
stable patient with retropharyngeal abcess
polymicrobial
clue for early congenital syphilis(5)
hepatosplenomegaly cutaneous lesion jaundice anemia rhinorrhea
xray in congental syphilis(2)
metaphyseal dystrophy
periostitis
late manifestation of congenital syphilis (7)
2 years frontal bossing high arched palate hutchinson teeth intersticial keratitis saddle nose perioral fissures
screening test for syphilis(3)
VDRL
RPR
Enzyme immunoassay
confirmatory test for syphilis(3)
FTA-ABS
TPPA=traponema particle agglutination assay
in the vignette the clue for syphilis congenital
ulcerative on his feet
3 phases of pertussis
catarrhal
paroxysmal
convalescent
immunisation in pertusis(2)
5 doses of Tdap from 2 months and 6 years
TDAP booster age 11-18 and during pregnancy
CBC in pertussis
lymphocyte predominant leukocytosis
does immunization protects for life
no immunity doen not provide lifelong immunity
confirmatory dx of pertussis(2)
bacterial culture
PCR
rx of pertussis
macrolides
complication of pertussis(5)
pneumonia weight loss subonjonctival hemorage pneumothorax respiratory failure and deat
clue in catarrhal phase
mild cough
rhinitis
duration of catarrhal phase
1-2 weeks
clue for paroxysmal phase(4)
20-30 mn coughing paroxysms
inspiratory whoop
staccato cough
posttussive emesis
duration of paroxysmal phase
2 - 6 weeks
clue for convalescent phase(2)
cough and
post tussive emesis resolve
duration of convalecent phase
weeks to months
osteomyelitis in sickle cell disease(2)
salmonella # 1
staph aureus
important clue to dx pertussis
inadequate vaccination
predisposing factor for sinusitis
viral upper respiratory infection
clue for sinusitis(4)
erythema and swelling of the nasal turbinates
purulent drainage
congestion
cough
quid of preseptal cellulitis
mild infection of the eyelid anterior to the orbital septum
quid of orbital cellulitis
seriuos infection post to the orbital septum
clue to distinguish preseptal from orbital cellulitis
ophtalmoplegia in orbital cellulitis(diplopia)
eye problem in orbiatl cellulitis(4)
decreased visual acuity
diplopia
ophtalmoplegia
proptosis
dangerous complication of orbital cellulitis(4)
blindness
intracranial infection
orbital abscess
cavernous sinus thrombosis
characteristic of non inflammatory joint fuid(3)
clear
200-2000 wbc
25% PMN
example of non inflammatory joint disease
OA
characteristics of inflammatory joint fluid(3)
translucent and opaque
2000-100000 wbc
often> 50% PMN
example of inflammatory joint disease(2)
crystal
RA
characteristics of septic joint(3)
opaque
50 000-150 000 WBC
often 80%-90 %
first bug in septic joint
staph aureus
rx of septic joint(2)
IV antibiotics
emergency surgical drainage
complication of septic joint
permanent joint destruction
most frequent complication of mumps
orchitis
febrile illness with development of rash 1 day after taking amox which infection should be suspected and dx(2)
epstein barr virus
post antibio rash
triad in Mononucleosis infection(3)
exsudative tonsillitis or pharyngitis
posterior or diffuse cervical lymhadenopathy
fever
presentation of post antibiotoc rash(2)
polymorphous
maculopapular
break time in sport during mononucleosis
> ou egal a 3 semaines
common oropharyngeal lesions in kid(5)
aphtous stomatitis herpangina herpes gingivostomatitis group A streptococal pharyngitis infectious mono
quid of aphtous lesions or canker sores(2)
reccurent ant oral mucosa ulcers
no fever
localisation of ulcers in canker sores(4)
lips
cheeks
mouth floor
ventrum of the tongue
clue for herpangina(2)
vesicles and ulcer on post oropharynx
fever
clue for gingivostomatitis
vesicles and ulcer on ant oropharynx
fever
clue for group A strep pharyngitis(3)
tonsillar exsudates
fever
anterior cervical lymphadenopathy
cause of unilateral cervical adenitis in children(5)
staph aureus and staph pyogenes anaerobic bacteria non tuberculos bacteria Mycobacterium TB bartonella henselae
clue for adenitis induced by staph and strep(2)
associated cellulitis
or
suppuration
rx of adenitis induced by staph or strep
clindamycin
incision and drainage
risk factor for anaerobic bacteria induced adenitis(2)
dental caries
periodontal disease
rx of anaerobe adenitis(2)
clindamycin
augmentin
clue for non TB mycobacteria adenitis
rarely tender
rx of non tb mycobacteria adenitis(2)
excision
macrolide +/- rifampin
clue for adenitis caused by bartonella hensellae
exposure to kittens or cats
rx for adenitis caused by bartonella hensellae
no needed
contraindication to rotavirus vaccination(4)
history of antissuception
anaphylaxis to vaccine ingredients
history of uncorrected congenital malformation in the GI like Meckel
severe combined immunodeficiency
age for administration of rotavirus
2-6 months
management of cat bite
augmentin pendant 5 jours
most common cause of osteomyelitis in kid
staph aureus
most common cause of acute tender lymph node in kids
staph aureus
clue for rhinosinusitis(3)
persistent symptom> ou egal a 10 jours without improvement
or
severe symptoms including fever> ou egal 39,purulent discharge or face pain> ou egal a 3 days
or
worsening symptoms > ou egal a 5 jours after initially improving viral upper respiratory infection
bugs causing rhinosinusitis(2)
step pneumoniae
nontypeable haemophilus influenzae
rx of choice of bact rhinosinusitis
augmentin
step in management of septic joint with effusion(4)
Labs de routine
xray
arthrocentesis
(in some vignette arthrocentesis is more important than Xray)
osteomyelitis in kid less than 3 years(3)
staph
group B streptococcus
gram negative bacilli
osteomyelitis in kid more than 3 years(3)
staph aureus
group A streptococci
strep pneumo
rx of osteomyelitis in kid less than 3(2)
nafcillin or vancomycin
plus
gentamycin or cefotaxime
rx of osteomyelitis in kid more than 3(4)
nafcilin or clindamycin or cefazolin or vancomycin
quid of howel jolly bodies(2)
single round blue inclusions on wright stain
nuclear remnants
quid of aplastic anemia
everything is low
acquired cause of aplastic anemia(6)
drugs toxic chemicals idopathic viral infection immune disorder thymoma
drugs causing aplastic anemia
NSAIDS
sulfonamides
toxic chemicals causing aplastic anemia(2)
benzene
glue
congenital cause of aplastic anemia
fanconie anemia
inheritance of fanconi(2)
autosomal recessive
or xlinked
risk in fanconi
cancer by the age of 16
Dx of fanconi
chromosomal breaks
clue for fanconi(4)
congenital marrow failure
poor growth
morphologic abnormalities
macrocytic anemia
disease with cafe au laits spots(2)
fanconi
neurofibromatosis
eyes and ears problem in fanconi(3)
strabismus
lot set ears
middle ear abnormalities
middle ear abnormality in fanconi(4)
hemorrgae
incomplete development
chronic infections
deafness
definitive rx in fanconi for the anemia
hematopoietic stem cell transplantation
most common complication of sickle cell disease
painless hematuria
why patient will sickle cell disease pee a lot at night
isisthenuria=inability to concentrate urine
kid with foot refent foo woung you decide to vaccinate for tetanos mother who is the guardian accepts but the father not what to do
administer the vaccine
in case of separated couple how do you proceed for the consent
the consent of one parent or the guardian is sufficient to perform
clue for wiskott aldrich syndrome(3)
low platelet
plus eczema
plus reccurent bacterial infection
cause of thrombocytopenia in wiskott
decreased platelet production
platelet in wiskott aldrich
small
inheritance of aldrich wiskott
x linked
clue for acute lymphoblastic leukemia(5)
bone pain lymphadenopathy hepatosplenomegaly pallor from anemia petechia from throbocytopenia
dx of acute lymphoblastic leukemia
bone marrow biopsy with >25 % lymphoblasts
most common cancer in childhood
ALL
peak of ALL
2 - 5 ans
rx of ALL
chemotherapy
clue in the USMLE for ALL(2)
infant
high WBC
nosebleed and congestion in a patient with CT shows visible mass at the back of the left nostril and erosion of the adjacent bone dx
angiofibroma
male adolescent with epistaxis and bone erosion on the back of the nose
angiofibroma until proven otherwise
when to rx angiofibroma(3)
if juvenile angiofibroma is enlarging
obstructing the airway
cause chronic nosebleeds
surgery in angiofibroma
risk of recurrence
xray in osteosarcoma of humerus(2)
sunburst periostal reaction
codman triangle
the most common bone tumor in kid and young adults
ostosarcoma
bone of predilection of osteosarcoma
long bone
quid of codman triangle
periostal elevation
rx of osteosarcoma(2)
tumor excision
chemotherapy
when to suspect herediatary spherocytosis(4)
coombs negative
hemolytic anemia
splenomegaly in the setting of reticulocytosis hyperbilirubinemia spherocytosis and family history of anemia
confirmatory dx of hereditary spherocytosis
eosin 5 maleimide and acidified glycerol lysis tests
stroke in kid next step
peripheral smear and reticulocyte count
stroke in kid cause
SCD
physiopatho of stroke in SCD(3)
unknown but we think
red blood cell adherence to endothelium
activation of von willbrand’s factor’s
hyperviscosity
patient with history of easy bruising develops knee swelling after trauma first step
platelet count and coagulation studies
3 clue for bleeding disorders
prolonged bleeding after dental or minor procedures
bruising at pressure points
hemarthrosis
cause of bleeding disorder(4)
hemophilia A
hemophilia B
von willebrand disease
platelet function disorder
disease with platelet dysfunction(2)
bernard souilier
glanzman thromboasthenia
patient knee pain and swollen without trauma xray show central lytic lesion onion skinning appearrance dx
ewings sarcoma
type of tumor in erwing sarcoma
malignant
xray in erwing sarcoma(3)
onion skin, lamelated appearance
with a moth eaten or mottled appearance and extension in soft tissue
dx differenciel in erwing sarcoma
osteomyelitis
lieu for metastasis in erwing cell sarcoma(2)
lung
lymph nodes
patient with reccurrent sinopulmonary infection and diarrrhea since childhood develops anaphylactic transfusion reaction after blood transfusion cause of that
IgA deficiency
confirmatory dx of IGA deficiency(2)
low IGA level
normal IGM and IGG
prevention of infection and death in SCD(2)
give PNC prophylaxis
plus
pneumococcal vaccination
admistration of PNC in SCD
twice a day
until they reach five yo
factors of coagulation missing in cystic fibrosis(3)
vit K dependent
2, 7,9 ,10
protein C et S
why you have problem of bleeding in cystic fibrosis(2)
pancreatic insufficiency
problem in liposoluble vit absorbtion
toddler with unilateral firm mass and hematuria
tumeur de wilms(nephroblastoma)
peak for wilms tumor
2-5 ans
associated syndrome with wilms tumor(3)
wagr
beckwith wiedman syndrome
denys drash syndrome
quid of WAGR syndrome(4)
wilms tumor
aniridia
genitourinary anomalies
retardation mental
most common primary renl neoplasm in kid
wilms
dx of wilms(2)
1- contrast enhanced CT
2- chest xray for metastasis
rx of wilms(3)
tumor excision or nephrectomy
chemo
+/- radiation therapy
prognosis for rx wilms
5 year survival rate with rx :90%
role of hydroxyurea
increase fetal Hb
side effect of hydroxyurea(3)
leukopenia
anemia
thrombocytopenia
bref marrow suppression
marrrow suppression with hydroxyurea
temporary
polycythemia in newborn quid
central nervous hematocrit level greater than 65%
cause of polycythemia in newborns
delayed clamping of the umbilical cord
risk foor neonate in polycythemia(3)
respiratory distress
poor feeding
neurologic manif
clue for ALL(4)
more then 25 % de lymphoblast
lymphoblast lacks of peroxydase positive granules
but contain periodic acid schiff positive material
immunostaining for terminal deoxynucleotidyltransferase
immunostaining in ALL
TDT expression dans 95% des cas
cells expressing TDT(2)
pre T lymphoblastes
Pre B lymphoblastes
SCD patient with hip pain first dx
osteonecrosis(avascular nerosis)
mosr common affected bone in osteonecrosis in (2)
humerus
fever
patient with SCD presenting with dyspnea fatigue Hg: hb 4,5 wbc: 10000 platelets:300 000 reticulocytes=0,1% dx
aplastic crisis
low HB in SCD causes (3)
aplastic crisis
hemolysis
splenic sequestration
differentiate aplastic crisis from aplastic anemia
aplastic anemia =pancytopenia in a patient without SCD
characteristics of iron deficiency anemia(8)
Hmt< 30% RDW increased total RBC decreased low serum iron ferritin increased TIBC responds to iron supplementation normal electrhoresis no target cells
characteristics of alpha thalassemia anemia(8)
Hmt.> 30% RDW normal total RBC normal normal to increased serum iron ferritin TIBC normal no responds to iron supplementation normal electrophoresis target cells
characteristics of beta thalassemia anemia(8)
Hmt.> 30% RDW normal total RBC normal to increased normal to increased serum iron ferritin TIBC normal no responds to iron supplementation electrophoresis=elevated hb A2 target cells
shistocytes in the settting of bloody diarhea administration of antibiotics,low Hb low platelet and high creat
microangiopathic hemolytic anemia
bugs involved in hus(5)
E coli 0157h7 shigella campylobacter salmonella yersinia
peripheral smear in HUS
schistocytes
continuous flow murmur in left sternla border in young child (son)
Patent ductus arteriosus
knee chest position of in fallot how it will improve cyanosis (2)
increased systemic vascular resistance
increases pulmonary blood flow
viral prodrome(rhinorrhea,fever) and heart failure
viral myocarditis
chest xray in viral myocarditis(2)
cardiomegaly
pulmonary edema
ECK in viral myocarditis
sinus tachycardia
echo in viral myocarditis(2)
decreased ejection fraction
diffuse hypokinesis
Biopsin in viral myocarditisdium with myocite necrosis(2)
gold standard
inflammatory infiltrate of the myocardium with myocite necrosis
prognosis of viral myocarditis in newborns
mortality 75%
prognosis of viral myocarditis in older infants and children
mortality in 25%
out come in viral myocarditis
full recovery within2-3 months 66%
dilated cardiomyopathy /chronic heart failure 33%
what dysfunction you have in viral myocarditis
systolic and diastolic
management of viral myocarditis(3)
ICU
to reduce the risk of acute decompensatio
fatal arythmia
antibiotics used in rheumatic fever prophylaxis
IM PNC G given q 4 semaines
duration of prophylaxis of rheumatic fever without carditis
5 years or until the patient reaches 21 yo
duration of prophylaxis of rheumatic fever with carditis but no residual heart or valvular disease clinical or by echo
10 years or until the patient reaches 21 yo
duration of prophylaxis of rheumatic fever with carditis and persistent heart or valvular disease
10 years or until 40 yo
why you give PNC in patient rheumatic fever(2)
to prevent recurrent group A streptococcus pharyngitis
limit progression of rheumatic heart disease
patient one day old comes for cyanosis ,pulse oxymetry 80% with no improvement with 100% inspired o2.continuous machine like murmur is heard on auscultation oral mucosa is blue dx
cyanotic heart disease
central cyanosis plus 70-90% oxygen saturation dx
cyanotic heart disease
what to do in front of cyanotic heart disease
prevent closure of ductus arteriosus by giving prostaglandine E 1
PDA dependent congenital heart disease(5)
coarction of the aorta D transposition of the great arteries hypoplastic left heart syndrome total pulmonary venous connection tricuspid atresia
cause of supraventricular tachycardia in adolescent
WPW
mechanism involved in WPW
accessory atrioventricular pathway
EKG of WPW(3)
shortened PR interval
delta waves
widening qrs complex
clue for tricuspid atresia
left axis deviation
decrease pulmonary markings on chest xray
why tricuspid atresia you have decrease pulmonary markings on chest xray
due to hypoplasia of the right ventricle and pulmonary outflow tract
neonatal with EKG shwsleft axis deviation
it’s never normal
quid of tricuspid atresia
cyanotic heart disease
post pericardiotomy syndrome
pericardial effusion occurring within days or months after cardiac surgery
cardiomegalie with hypotension tachycardia muffled heart sound after surgery
pericardial effusion
most common heart malformation
VSD
clue for VSD
holosystolic murmur in left sternal border
plus
apical diastolic rumble
when will you have cyanosis in VSD
eisenmenger syndrome
quid of eisenmenger syndrome(2)
right to left shunt
unrepaired large VSD causes permanent pulmonary Hypertension and right to left shunt
cause of diastolic rumble in VSD at the apex
increased flow across the mitral valve
patietn 5y0 with asymptomaticgrade 2 left sternal border systolic ejection murmur best heard when the child is lying down and decreases with standing dx
benign chilhood murmurs
what to do in benign childhood murmur
observation
characteristics of inocent murmur(6)
asymptomatic no structural heart disease associated grade 2/6 early or mid systolic decreases with standing and valsalva have a normal associated s2
characteristics of pathologic murmur(6)
syptomatic structural heart disease associated grade 3/6 or higher hars and holosystolic or diastolic increases with standing and valsalva loud s2 fixed s2 splitted
adolescent losing consciousness after crying or anytime she gets frustrated .EP normal dx and rx
breath holding spell
reassure the patients
type of breath holding spell(3)
pallid =patient pale
cyanotic=
mixed=cyanose plus seizure/pallid plus seizure
stridor improving with neck extension chez 1 patient de moins d’un an with cardiac abnormalities no improvement with epinephrine corticosteroids or bronchodilators
vascular ring
where can you have vascular rings(2)
trachea=stridor wheezing
esophagus=dysphagia
age pour vascular ring
mois d’un an
risk in long Qt syndrome(3)
syncope
ventricular arythmia
sudden cardiac death
medication used in prevention of death in long Qt syndrome(2)
betablocker
pacemaker
what a patient with long qt syndrome should avoid(2)
electrolyte derangement
medications that block K+ channels
ventricular arythmia in long Qt syndrome
torsade de pointes
congenital cause of long Qt syndrome(2)
Jervell and lange nielsen syndrome=autosomal recessive
romano ward syndrome=autosomal dominant
jervel and lange nielsen syndrome(3)
family history of sudden death
congenital neurosensorineural deafness
qt interval=600ms
what happen in jervell and lange nielsen syndrome
molecular defect in potassium channels
rx of JLN syndrome(3)
refrain from vogorous exercice
maintaining normal ca++,K+and Mg++
avoid medication that can lengthen the qt interval
metabolic derangements causing long Qt syndrome(3)
hypocalcemia
hypoK+
hypoMg++
antibiotics induced long qt syndrome(2)
macrolide
fluoquinolone
psychotics meds induced long qt syndrome(3)
antipsychotics
TCA
SSRI
opioids meds induced long qt syndrome(2)
methadone
oxycodone
antiemetics meds induced long qt syndrome(2)
ondansetron
granisetron
antiarythmics meds induced long qt syndrome(5)
quinidine procainamide flecainide amiodarone sotalol
Qt interval
debut qrs a fin onde T
scaly rash in eyebrows nasolabial fold and scalp dx
seborrheic dermatidis
rx of seborheic dermatidis(3)
moisturisers
antifungals
topical steroids
quid cradle cap
seborrheic dermatidis
platelet in henock shonlein purpura
normal
problem in henock shonlein purpura
IGA mediated vasculitis
clue for Henock shonlein purpura(4)
palpable purpura on lower extremities
abdominal pain
arthralgia
renal involvement
atopic dermatitis in infant(2)
pruritis
skin lesions
skin lesions in atopic dermatitis localisation(4)
face
scalp
extensor surfaces
diaper region is spared
rx of atopic dermatitis in kid
improve the skin barrier function through the use of mild cleanserss and thick bland emollients in addition to mild topical antiinflammatory ointments
Tinea corporis=date
erythematous scaly pruritic rash with central clearing
rx of tinea corporis
topical antifungals