Pediatrics Flashcards

1
Q

Ophtalmia Neonatorum Day2

A

Neisseria Gonorrheae G(-) diplococci
Prevent with ointment
Tx Ceftriaxone

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2
Q

Ophtalmia Neonatorum Day 7

A

Chalmidia Trachomatis
Not effectively prevented by prophylaxis ointments
Tx Azythromycin PO

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3
Q

Ophtalmia Neonatorum Day 21

A

Herpes Simplex
Tx Systemic Acyclovir and topical Vidarabine

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4
Q

The most commonly tested disorders in the new born

A

G6PD deficiency
Phenylketonuria (PKU)
Galactosemia
Congenital Adrenal Hyperplasia
Congenital hypothyroidism
Hearing test
Cystic fibrosis

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5
Q

G6PD Deficiency

A

X-Linked Recessive characterized by Hemolytic crisis
Tx Reduce oxidative stress and specialized diets

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6
Q

Phenylketonuria PKU

A

AR
Deficiency in Phenyalanine Hydroxylase (PAH)
Leads to intellectual disability
Tx special diet low in phenyl alanine for at least the first 16 years of the patients life

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7
Q

Galactosemia

A

Rare genetic disorder that precludes normal metabolism of galactose and cause cataracts.
Tx cut out all lactose containing products.

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8
Q

Congenital adrenal hyperplasia (CAH)

A

AR
Resulting in errors of steroidogenesis
Tx replace mineralocorticoid and glucocorticoid deficiency and possible genital reconstructive surgery

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9
Q

Congenital Hypothyroidism

A

Compromises brain development
Must have normal thyroid function for brain development

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10
Q

Hearing test

A

Excludes congenital sensory - neural hearing loss
Necessary for early detection to maintain speech patterns and asses the need for cochlear implantation

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11
Q

Cystic fibrosis

A

Autosomal disorder
Thick mucus
Best initial test -> Sweat Chloride
Most Accurate -> Genetic Analysis of the CFTR gene.

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12
Q

Mothers with HBsAg +
Child should receive

A

Hep immunoglobulin (HBIG) + vaccine

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13
Q

Thyroglossal duct cyst

A

Midline and moves with swallowing
Becomes symptomatic after a respiratory infection
Tract between foremen cecum and base of the neck

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14
Q

Dermoid cyst

A

Midline cystic mass with trapped epithelial debris
Does not change with tongue movement or saying ahh

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15
Q

Brachial cleft cyst

A

Most common type SECOND Brachial cleft lesion
Located inferior to the angle of the mandible and anterior to the esternocleidomastoideo muscle

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16
Q

Cystic hygroma

Macrocystic lymphatic malformations

A

Translucent soft mask covered by normal skin
Common location: cervical facial lesion, axilla, lateral chest wall
Associated with Down syndrome

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17
Q

Thymic cyst

A

Located at midline between angle of the mandible and midline of the neck

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18
Q

Thymic cyst

A

Located at midline between angle of the mandible and midline of the neck

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19
Q

ACE Inh Neonate

A

Craniofacial abnormalities

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20
Q

Anesthetic in neonate

A

Respiratory and CNS deppression

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21
Q

Barbiturates in neonate

A

Respiratory and CNS depression, dilated pupils.
Phenobarbital is associated with vitamin K deficiency

22
Q

Diethylstilbestrol (DES)

A

Clear cell adenocarcinoma (CCA) of the vagina or cervix

23
Q

Isotretinoin

A

Facial and ear abnormalities, congenital heart disease

24
Q

Magnesium Sulfate in the neonate

A

Respiratory depression

25
Q

NSAIDS IN NEONATE

A

Premature closure of Ductus arteriosus

26
Q

Phenytoin

A

Hypoplastic Nails, typical facies, IUGR

27
Q

Sulfonamides in Neonate

A

Displaces bilirubin from albumin

28
Q

Tetracycline in neonate

A

Enamel hyperplasia, discolored teeth

29
Q

Valproate / carbamazepina

A

Intellectual disability, neural tube defects

30
Q

Warfarin in newborn

A

Facial dimorphism and condrodysplasia, bone stippling

31
Q

Congénital toxoplasmosis pathogenesis

A

Maternal consumption of undercooked meat
Inadvertent ingestion of cat feces

32
Q

Congenital toxoplasmosis

A

Chorioretinitis
Diffuse intracranial calcifications
Macrocefaly (hydrocephalus or microcephaly)
Seizures

33
Q

CONGENIATAL CMV PATHOGENESIS & Features

A

Maternal contact with infected bodily fluids (saliva)
Chorioretinitis
Periventricular intracranial calcifications
Microcephaly
Sensorineural hearing loss

34
Q

Congenital toxoplasmosis Dx & Tx

A

Toxoplasma serology or CPR
Pyrimethamine, sulfadiazine, folinic acid

35
Q

CMV Dx & Tx

A

Urine or saliva CMV PCR
GANCICLOVIR
VALGANCICLOVIR
If symptomatic.

36
Q

Congenital heart defect that typically presents within the first 24hours of life with cyanosis and a single loud S2

A

Transposition of the great vessels

37
Q

Pulsus Alternans

A

Sign of left ventricular dysfunction

38
Q

Pulsus bigeminus

A

Sign of HOCM

39
Q

Pulsus bisferiens

A

In aortic regurgitation

40
Q

Pulsus tardus et Parvus

A

Aortic stenosis

41
Q

Pulsus paradoxus

A

Cardiac tamponade
Tension pneumothorax

42
Q

Irregularly irregular

A

Atrial fib

43
Q

Irregularly irregular

A

Atrial fib

44
Q

Combination of hearing loss, syncope, normal vital signs and physical exam and
The family history of sudden cardiac death

A

Consistent with long QT syndrome

45
Q

Combination of hearing loss, syncope, normal vital signs and physical exam and
The family history of sudden cardiac death

A

Consistent with long QT syndrome

46
Q

best treatment for Long QT syndrome

A

Beta blocker METOPROLOL

47
Q

How beta blockers may shorten the QT interval

A

By decreasing activation from the left stellate ganglion and reducing cardiac excitation during exertion

48
Q

The only beta blocker that prolongs QT interval

A

SOTALOL

49
Q

However progressive symptoms leading to dilated cardiomyopathy with secondary mitral regurgitation can cause :

A

S3 Gallop and holosystolic murmur

50
Q

Tourette Syndrome Tx

A

Behavioral Therapy (habit reversal training)
Anti Anyidopaminergic agents
—> Tetrabenazine (dopamine depleter)
—> Antipsychotics (Rc Bockers)
Alpha 2 Adrenergic receptor agonist.