Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharm II Test 2 > Pediatric Psych Treatment > Flashcards

Pediatric Psych Treatment Flashcards

1
Q

Stimulants- Available Drugs

A

Methlyphenidate
Dexemethylphenidate
Amphetamine Salts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Stimulants- Mech of Action

A

Block reuptake of NE and DA in presynaptic neurons

Increase DA in synaptic cleft

Da improves attention
NE dampens noise, increases inhibition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Stimulants- Absorption, Distribution

A

Can be short or long acting
Titrate to optimum dose
MPH has faster onset, but Adderall (amphetamine salts) has longer lasting effect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Stimulants- Adverse Effects/Contraindications

A

Black box warning= chance of sudden death–> contraindicated in structural cardiac abnormalities, cardiomyopathy, serious rhythm abnormalities

temporary growth slowing

Adderall= more stomachaches and sad mood than MPH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Methylphenidate- Clinical Use

A

first line for ADHD

patients at least 6 y/o

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Amphetamine salts- Notes

A

Patients at least 3 y/o

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Methylphenidate- Brand Names

A 
Ritalin
Ritalin LA/SA 
Metadate CD/ER
Concerta
Daytrana
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Dexemthylphenidate- Brand Names

A

Focalin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Amphetamine Salts- Brand Names

A

Dextroamphetamine
Mixed amphetamine salts- ADDERALL
Vynase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Non-Stimulants (Selective NE Reuptake Inhibitors)- Available Drugs

A

ATOMOXETINE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Selective NE Reuptake Inhibitor (Atomoxetine)- Mech of Action

A

Inhibit presynaptic NE transporter, Increase NE in synaptic cleft.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Selective NE Reuptake Inhibitor (Atomoxetine)- Absorption, Distribution

A

dosed by weight

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Selective NE Reuptake Inhibitor (Atomoxetine)- Clinical Use

A

suggested second line for ADHD

patients at least 6 y/o

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Selective NE Reuptake Inhibitor (Atomoxetine)- Adverse Effects/Contraindications

A

caution in children that are Cyp2D6 slow metabolizers= higher peak concentrations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

SSRIs- Available Drugs

A 
FLUOXETINE
Citalopram
ESCITALOPRAM
FLUVOXAMINE
SERTALINE
Paraoxetine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

SSRIs- Mech of Action

A

increase 5-HT in the synaptic cleft

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

SSRIs- Adverse Effects/Contraindications

A

Black box warning= increased risk of suicidal thinking and behaviors during first few months of treatment

18
Q

Fluoxetine- Clinical Use

A

MDD- age >8y/o

OCD- age >7y/o

19
Q

Escitalopram- Clinical Use

A

MDD- age 12-17

20
Q

Fluvoxamine- Clinical Use

A

OCD age >8y/o

21
Q

Sertaline- Clinical Use

A

OCD age >6y/o

22
Q

Citalopram, Escitalopram- Notes

A

Most selective for 5-HT, no effect on NE

23
Q

Sertaline, Paroxetine- Notes

A

Most potent 5-HT reuptake inhibitors

24
Q

SNRIs- Available Drugs

A

Venlafaxine
Mirtazapine
Duloxetine
Desvenlafaxine

25
Q

SNRIs- Mech of Action

A

increase 5-HT, DA, and NE in the synaptic cleft

26
Q

SNRIs- Clinical Use

A

off-label use only

27
Q

SNRIs- Adverse Effects/Contraindications

A

Black box warning= increased risk of suicidal thinking and behaviors during first few months of treatment

28
Q

Typical Antipsychotics- Available Drugs

A

Haloperidol
Chlorpromazine
Thioridazine

29
Q

Typical Antipsychotics (Haloperidol, Chlorpromazine, Thioridazine)- Mech of Action

A

Block postsynaptic D2 receptors and presynaptic dopamine autoreceptors

30
Q

Typical Antipsychotics (Haloperidol, Chlorpromazine, Thioridazine)- Clinical Use

A

Acute, short-term for aggression, delirium, or when treatment with atypical antipsychotics fail

31
Q

Typical Antipsychotics (Haloperidol, Chlorpromazine, Thioridazine)- Adverse Effects/Contraindications

A

NMS (NEUROLEPTIC MALIGNANT SYNDROME)

Contrindicated in prolonged QT interval, ventricular tachycardia, arrhythmias

32
Q

Atypical Antipsychotics- Available Drugs

A 
RISPERIDONE
Clozapine
Olanzapine
Quetiapine
Ziprasidone
Aripiprazole
33
Q

Atypical Antipsychotics (RISPERIDONE, Clozapine, Olanzapine, Quetiapine, Ziprasidone, Aripiprazole)- Elimination

A

metabolized by CYP450 system

34
Q

Atypical Antipsychotics (RISPERIDONE, Clozapine, Olanzapine, Quetiapine, Ziprasidone, Aripiprazole)- Adverse Effects/Contraindications

A

NMS (NEUROLEPTIC MALIGNANT SYNDROME)

safer than the typical antipsychotics

Risperidone- increased appetite, fatigue, dizziness, drooling

Contraindicated in prolonged QT interval, ventricular tachycardia, arrhythmias

35
Q

Lithium Carbonate- Mech of Action

A

Blocks Phosphoinositol (PI) activity
Inhibit cAMP
Stabilize neuronal excitement

36
Q

Lithium Carbonate- Elimination

A

Excreted unchanged by the kidney

Children have higher clearance & shorter half life than adults= reach steady state faster

37
Q

Lithium Carbonate- Clinical Use

A

First line treatment for bipolar in children- age >12
irritability
impulsivity
aggression

may have protective effect against suicidality

38
Q

Lithium Carbonate- Adverse Effects/Contraindications

A

GI symptoms, polyuria, polydipsia, enuresis, fatigue, fine hand tremor, osmotic diarrhea

Contraindicated in renal disease, cardiovascular disease, dehydration, hyponatremia, co-administration of diuretics or ACE inhibitors

39
Q

Antiepileptics- Available Drugs

A 
DIVALPROEX SODIUM
Carbemazepine
Oxacarbazepine
Lamotrigine
Topiramate
Gabapentin
40
Q

Divalproex Sodium- Clinical Use

A

First line treatment for Bipolar in children- age >18
irritability
impulsivity
aggression

41
Q

Divalproex Sodium- Adverse EffectContraindications

A

GI symptoms, weight gain, drowsiness, hair loss
hepatotoxicity, liver failure
rarely pancreatitis, thrombocytopenia, polycystic ovaries

Pharm II Test 2 (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions