Pediatric Immunizations Flashcards
What is the vaccine described by the brand names Infanrix and Daptacel?
DTaP
What is the vaccine described by the brand name Adacel and Boostrix?
Tdap
What is the vaccine described by the brand names Tenivac and Tdvax?
Td
What is Kinrix?
DTaP + IPV
What is Quadracel?
DTaP + IPV
What is Pentacel?
DTaP + IPV + Hib
What is Pediatrix?
DTaP + IPV + HepB
What is ProQuad?
MMRV
What is Twinrix?
HepA + HepB
What is MenHibrix?
MenCY + Hib
What is VAXELIS?
DTaP + IPV + Hib + HepB
What is the minimum interval required between live vaccines, if not given simultaneously?
28 days
What happens when a vaccine is given 5+ days before the minimum dosing interval or age?
The dose will not count and should be repeated
What happens when a vaccine is due to be given past the intended interval timeframe?
It should be given at the next visit, avoid restarting vaccine series
What should you do if a dose is not reported in the vaccine record?
Re-dose.
Which vaccines should be given during pregnancy?
- IIV4
- Tdap
- RSV (Abrysvo)
- COVID-19
Consider waiting until the ____ trimester before giving inactivated vaccines during pregnancy
2nd
Which vaccines are contraindicated in pregnancy?
- MMR
- Varicella
- HPV
- LAIV
How should live vaccines be given with regard to chemo/radiation therapy?
2 weeks before or 3 months after treatment
How should live vaccines be given with regard to steroid therapy >2mg/kg/day or >20mg prednisone >14 days
Wait a month after discontinuation
How should live vaccines be given with regard to high-dose steroids <14 days
Can vaccinate following discontinuation or wait 2 weeks after
What type of vaccines are tetanus and diphtheria?
Toxoid
How should live vaccines be given with regard to IVIG therapy?
At least 3 months before and 2 weeks after IVIG
How long should you hold live vaccines following IVIG for Kawasaki disease?
11 months
How should live vaccines be given with regard to PPD tests?
Simultaneously or wait 4-6 weeks to place PPD
How should live vaccines be given with regard to antiviral treatments?
Avoid therapy 48 hours prior or 14 days after vaccination
Which vaccines can be given SC?
Zostavax, MMRV, Polio, and Meningococcal or Pneumococcal polysaccharide vaccines
How effective is DTaP and Tdap?
DTaP is 80-90% effective
Tdap is 70% effective
What is the age range for different diphtheria vaccinations?
Age <7: DTaP or DT
Age 7+: Td
Age 11+: Tdap
When should tetanus boosters be given?
Every 10 years if no injury
Every 5 years if at risk
In the case of severe injury, 1 year after last dose
What is a contraindication to DTaP besides allergy?
History of encephalopathy within 7 days of pertussis vaccination
Which patients >12-15 months old should get the Hib vaccine?
- Chemo/radiation
- Immunodeficiency
- Asplenia
What is the efficacy of the HepB vaccine?
90-95% persistent protection
How should HPV be given to a 9-14 year old?
2 dose series, with the second dose given 6-12 months after the first
How should HPV be given to a patient 15 years or older?
3 dose series, with the second dose given 1-2 months after the first, and the third dose given 6 months after the first dose
How many doses of HPV should immunocompromised patients get?
3 doses, regardless of age
When is the influenza season?
Typically October to March/April
What type of change to influenza occurs annually and affects types A and B viruses?
Antigenic drift
What type of change to influenza occurs drastically and can result in epidemics or pandemics? (Affects type A virus)
Antigenic shift
What is the minimum age for the influenza vaccine?
6 months
What is the efficacy of the influenza vaccine typically?
45-50%
How should influenza be given to children <9 for their first lifetime dose?
Give 2 doses separated by 4 weeks
When can LAIV be used?
Healthy children and adults age 2-50 years
What immunity percentages are reached after the first dose of MMR?
93% measles & 78% mumps
What immunity percentages are reached after the second dose of MMR?
97% measles and 88% mumps
What can be done with MMRV to reduce seizure incidence?
Separation of MMR and V on the first dose
What should be given to a 6-12 month infant traveling internationally?
1 dose of MMR, dose not count for dose series
What should be given to an unvaccinated child >12 months traveling internationally?
2 doses of MMR separated by at least 4 weeks prior to travel
Why is MMR not usually given before 1st birthday?
Circulating maternal antibodies may interfere with protection
What happens with a mumps outbreak?
3rd dose of MMR is indicated
What are side effects of the Varicella vaccine?
- Maculopapular rash
- Rare febrile seizure risk with MMRV
- Transmission of varicella
What is the minimum age for Menveo (MenACWY-CRM)?
2 months
What is the minimum age for MenQuadfi (MenACWY-TT)?
2 years
A patient is given their first meningococcal dose at age 11-12, when should they get a booster?
Age 16
A patient is given their first meningococcal dose at age 13-15, when should they get a booster?
Age 16-18
A patient is given their first dose at age 16+, when should they get a booster?
No booster indicated
When is meningococcal recommended in high risk?
- HIV
- Asplenia
- Travel to epidemic regions
- Unvaccinated first-year college/military living in dorms
- Persistent complement component deficiency
Which brand name vaccines are MenB?
Bexsero and Trumenba
When is MenB indicated?
- Asplenia
- Persistent complement component deficiency
- Receiving complement inhibitors (eculizumab)
- Microbiologists regularly exposed to N. meningitidis
Which vaccine can be given for those needing both MenACWY and MenB?
Penbraya (Pfizer)
Age 10-25
Why is PPSV23 not effective in children <2?
It’s a polysaccharide vaccine
When is PPSV23 used?
Older children and adolescents with high-risk conditions with PCV15
What is the invasive risk decrease of PPSV23?
60-70%
A child, age 2-5 with a high risk condition has a history of <3 PCV doses, what should they get?
2 dose PCV >8 weeks apart
A child, age 2-5 with a high risk condition has a history of 3 PCV doses, what should they get?
1 dose PCV (8 weeks from last)
A child, age 2-5 with a high risk condition has not received PPSV23 or PCV20, what should they get?
1 dose PCV20 or PPSV23 (8 weeks from last)
What are the protection rates at different doses of IPV?
1 dose: 0%
2 doses: 95%
3 doses: 99%
4 doses: prolonged
How many doses is RotaTeq?
3 doses
How many doses is Rotarix?
2 doses
What is the required timeframe for the rotavirus series?
Must start by 15 weeks
Must complete by 8 months, 0 days
What is the minimum age for COVID-19 Pfizer + Moderna?
6 months
What is the minimum age for COVID-19 Novavax?
12 years
Which COVID vaccine should be stored ultra-cold?
Pfizer
What is a rare, possible side effect of the COVID-19 vaccine?
Myocarditis, specifically males age 12-17