Pediatric Hepatobiliary Disease

Question 1

Jaundice

Answer 1

(icterus) yellow discoloration of tissues due to abnormal deposition of bilirubin

Question 2

Physical exam findings of jaundice

Answer 2

skin, sclerae, mucous membranes

Question 3

Classification of jaundice

Answer 3

pre-hepatic, hepatic, post-hepatic

Question 4

kernicterus

Answer 4

toxic accumulation of unconjugated bilirubin in neonatal brain

Question 5

Treatment for physiologic jaundice

Answer 5

Phototherapy–expose to UV light in controlled way

• light isomerizes water insoluble bilirubin to water soluble so it can be excreted
• can also do transfusion but photo therapy usually