Pediatric Flashcards
Investigations for eating disorders
CBC, lytes, extended lytes, thyroid, LH/FSH, estradiol, prolactin, BHCG, ECG if abnormal lytes, bone density (family MD)
Hospitalization requirements for anorexia nervosa
< 75% ideal body weight or ongoing weight loss despite intensive MGMT, refusal to eat, body fat < 10%, HR < 50 at daytime, < 45 at night, sBP < 90, orthostatic change in pulse > 20 or > 10 in sBP, T < 35.6, arrhythmia
Hospitalization requirements in bulimia nervosa
syncope, K+ < 3.2, esophageal tears/hematemesis, arrhythmias, suicide risk, intractable vomiting
SSRI of choice for children
fluoxetine
Chlamydia treatment ABx
azithromycin 1 g PO or doxycycline 100 mg BID x 7 days
Complications of chlamydia
chronic pelvic pain due to PID, ectopic pregnancy, infertility, reactive arthritis, epididymo-orchitis
To r/o in bartholian cysts
malignancy, STI (gonorrhea)
Abx of choice for gonorrhea
ceftriaxone 250 mg IM or cefixime 400 mg PO x 1 an azithromycin 1g PO x 1
MGMT of gonorrhea
Abx, sexual abstinence for 7 days, f/u cultures within 4 - 5 days post-tx, repeat screening after 3 months (not done with chlamydia)
Causes of Cyanosis with 1st hours
ToF, ebstein’s, pulmonary atresia
Definition of Ebstein’s anomaly
tricuspid valve is displaced towards apex of RV
Causes of cyanotic congenital heart disease
ToF, ebstein’s anomaly, TGA, trucus arteriosis, tricuspid atresia, total anomalous pulmonary venous return (TAPVR)
5Ts of cyanotic congenital heart defects
ToF (overriding aorta, VSD, PA stenosis, RV hypertrophy), truncus arteriosus (single trunk for aortic arch, pulm arteries and coronary arteries), TGA (RV –> aorta and LV to PA), tircuspid atresia (forces systemic venous return across ASD –> mixing of pulmonic venous return), TAPVR: PV not connected to LA
definition of patent ductus arteriosus
persistent patency of structure between L pulmonary artery and descending aorta
Signs of CHF in pediatric patients
2Ts and megalies: tachycardia, tachypnea, cardiomegaly, hepatomegaly
Pathological/Abnormal fractures in children
< 18 months, non-ambulatory children, metaphyseal, rib, scapula, vertebrae, sternum
Disorders to r/o in child abuse
birth injuries, osteomalacia, congenital syphilis, bone disorders (ricket’s, osteogenesis imperfecta, NM disorders, copper deficiency)
Definition of macule
flat, circumscribed area of colour change, < 1 cm; if greater, patch
Definition of papule
elevated palpable lesion, if > 1 cm plaque
Definition of vesicle
fluid-filled elevation (i.e., pus), If > 1 cm = bullae
Definition of pustule
circumscribed elevation of skin containing purulent exudate
Definition of nodule
palpable solid lesion, if > 1 cm tumour
Key skin disorders in newborns (5)
acne neonatorum, erythema toxicum neonatoroum, infantile hemangioma, milia, transient neonatal pustular melanosis
Acne neonatorum
closed comedones on corehead, nose and cheeks, resolves with 4 months without scarring
erythema toxicum neonatorum
pustular eruption on face/trunk/proximal extremities, sparing palms and soles. flea-bitten appearance. resolves over 5 - 7 days usually but up to several weeks
infantile hemangioma
benign vascular tumour, red appearance, may grow rapidly but ultimately resolves by age 12 at the latest, 50% by age 5
milia
1-2 mm pearly white or yellow papules often seen on forehead, cheeks, nose and chin, self-resolving with 3 months of life
transient neonatal pustular melanosis
vesiculopustular rash, seen in black newborns, can involve palms and soles; self limiting
diaper rash definition
beefy red plaques and confluent erosions, + fine scales, +painful, satellite papules and pustules on thigh/abdomen, involving skin folds; MGMT: topical antifuncal 1% clotrimazole
contact dermatitis definition
shiny erythematous rash, macerations and erosions, skin folds are NOT involved (the line of the diaper); MGMT: barrier cream
Skin disorders of childhood (5)
scabies, impetigo, tinea, urticaria, molluscum contagiosum
Definition of exanthem
skin eruption + fever, always involves the mucosa (check the mouth)
Measles Presentation
morbiliform rash starting from hairline down (face/neck/trunk), 3Cs (conjunctiva, coryza, cough), koplik spots on buccal mucosa; infectious 4 days before and after rash requiring respiratory isolation, MGMT: vitamin A, Ig +MMR vaccine for contacts. complications: pneumonia, OM, encephalitis, myocarditis
Rubella presentation
pink maculopapular rash on face/neck/trunk, occipital and retroauricular nodes, low grade fever; MGMT: symptoms. complications: STAR - sore throat, arthritis, rash, congenital anomalites if during pregnancy (TORCH)
Roseola presentation
pink maculopapular rash (HHV-6), MGMT: symptoms. complications: febrile seizures
Erythema infectiosum presentation
parvovirus B19; slapped cheeks, can be provoked with exercise or sun exposure. MGMT: STAR, glove & stocking distribution, aplastic crisis in SCD
Chicken pox presentation
incubation is 21 days, ithcy vesiculobullous rash with crusts, dew drops on rose pedals; MGMT: symptoms, Complications: bacterial super-infections, necrotizing faschiitis, CNS: encephalitis, cerebellar ataxia, hepatitis, DIC
Herpes Simplex presentation
grouped vesicles with erythematous base; MGMT: topical or oral antivirals; Complications: encephalitis, hepatitis, skin infections, keratitis, gingivostomatitis, DIC
Hand-foot-mouth disease presentation
Coxsackie disease; vesicles and pustules with eruthematous base involving tongue, posterior pharynx. MGMT: symptoms. Complications: dehydration
Gianotti-Crosti syndrome
associated with EBV/HBV/coxsackie/parvovirus; acrodermatitis (involving hands and feet) papular, preceeding viral prodrome; MGMT: self-limiting
Scarlet Fever presentation
GAS: generalized red papules with sand-paper texture, flexural accentuation (pastia’s lines), desquamation, strawberry tongue, petechie on palate; MGMT: penicillin V/ampicillin/amoxicillin; complications: pneumonia, pericarditis, meningitis, hepatitis, glomerulonephritis, rheumatic fever
Kawasaki disease presentation
fever 5+ days and 4/5 of: unilateral LN, red/cracked lip/strawberry tongue, edema, erythema of palms and soles, generalized maculopapular rash, non-purulent bilateral conjunctivitis; MGMT: aspirin high-dose, IVIG, baseline ECHO and repeat in 6 months; complications: coronary artery aneursym
Dermatitis definition
red, inflammatory skin changes with poorly demarcated borders
Common types of dermatitis in pediatric patients (4)
contact dermaitits, atopic dermatitis (eczema), seborrheic dermatitis, nummular dermatitis, scabies
Eczema definition & MGMT
papules/plaques of edema and erythema +/- excoriation/lichenification, dry skin, pruritus; MGMT: skincare (emollients and moisturizers), topical corticosteroids for flare control (mid to high potency), lower potency for maintenace, topical calcineurin inhibitors
Distribution of eczema as per age group
infants: face + extensors
toddlers: flexural surfaces
adults: face, dorsum of feet, hands and eyelids
Eczema herpeticum definition & MGMT
severe and lethal complication of atopic dermatitis (eczema) due to superimposed HSV infection; Complications: blindness, mortality Sx: fever + grouped punched-out erosions; MGMT: high-dose systemic antiviral therapy, optho consult
Papulosquamous Disorders definition + common types in pediatric patients (4)
red, itchy, scaly lesions with well-defined borders, hyperkeratotic and well-demarcated; psoriasis, pityriasis rosea, tinea, corporis, drug eruptions
Psoriasis definition + MGMT
papulosquamous plaques with silvery scale; Auspitz sign: bleeding with removal of scales; nail involvement, arthritis, pruritus, involving extensor surfaces, scalp, genitalia, gluteal folds
Night terrors vs. nightmares
Night terrors: 1st third of the night, +autonomic agitation, high arousal threshold, agitated if awakened, no daytime sleepiness or recall of event; Nightmares: lasts 3rd of sleep (REM), +/- autonomic agitation, low arousal threshold, agitated after event, can have daytime sleepiness and frequent vivd recollection of event
Primitive Reflexes:
Root (0-4 months), Suck (0 - persists), Hand-toe grasp (0 - 3 months), Moro (0 - 6 months), asymmetric tonic neck reflex (2wks - 6 months), protective equilibrium (4 mos - persistent), parachute rection (8 months - persistent)
Pediatric hypoglycemia DDx
endocrine vs. non-endocrine; Endocrine ketosis, GH deficiency, panhypopituitarism, ACTH deficiency, addison’s disease, excess exogenous insulin; Non-endocrine: sepsis/shock, liver disease, ingestion, inborn error
signs and sx of hypoglycemia
tremors, sweating, weakness, tachycardia, nervousness, hunger, neuroglycopenic - lethargy, irritability, confusion, hypothermia, seizures, coma
Inv for hypoglycemia NYD
CBC+lytes, VBG, GH, cortisol, FFAs, beta-hydroxybutyrate, lactate, NH4, etc. ketones, substances
MGMT of hypoglycemia in infants:
treat if < 3.3 + symptoms or < 2.8 mmol/L; 5 mL/kg of D10W or 2ml?kg of D25W bolus, continuous dextrose to maintain glucose, if no IV access, glucagon IM or SC (0.03 - 0.5 mg/dose for children < 20 kg; 1mg/dose for > 20 kgs) q20 mins
SVT vs sinus tachy in pediatric patients
SVT: >220 BPM if < 1 yo; > 180 if > 1 yo
Definition of shock
inadequate blood flow and oxygen delivery to meet tissue metabolic demands
Signs of Compensated shock vs. Decompensated shock
Compensated: normal sBP, tachycardia, cool and pale distal extremities, delayed cap refill, weak peripheral pulses vs. central; decompensated: hypotension + depressed mental status, decreased U/O, metabolic acidosis, tachypnea, weak central pulses, colour changes (mottling)
Initial MGMT of Shock
ABCs: position the patient, optimize oxygen content, support ventilation, establish lines; frequent assessment of vitals, ancillary tests, specific treatments; INV: CBC, lytes, curea, Cr, glucose, CRP, lactate, ABG, VBG, blood cx, imaging
Trendelenburg improves circulation in shock: T or F?
false (CJEM 2004; Johnson et co): does not improve circulation, detrimental effects on RVEF, head injuries and IOP, aspiration, pulmonary disorders
Glucose MGMT for pediatric patients
**in all critically ill or injured children perform rapid glucose test to r/o hypoglycemia as a cause or contributing factor to poor clinical status: MGMT: newborns: D10W 5 - 10 mL/kg; infants and children: D25W 2 - 4 mL/kg; Adolescents: D50W 1-2 mL/kg
Hypoglycemia MGMT for pediatric patients: rule of 50s
D10W x 5ml/kg; D25W x 2 ml/kg; D50W 1 ml/kg
DDx for tachypnea in the newborn(9)
respiratory distress syndrome (RDS), transient tachypnea of the newborn (TTN), pneumothorax, meconium aspiration, hypoglycemia, hypothermia, cardiac abnormalities (cyanotic vs. noncyanotic), neonatal sepsis, congenital diaphragmatic hernia
H&P for respiratory distress in newborn
Birth history: C/S vs. SPV, maternal health factors, GBS, drug use, ROM prolonged?, maternal fever/infections, meconisum in amniotic fluid, birth weight, APGAR score
APGAR score
normal: 8+; A:appearance (pale, pink), Pulse (absent, below or over 100), grimace (floppy, responding to stimulation), activity (muscle tone), respiration (crying, slow, etc.)