PCOS

Question 1

What is the most common cause for infertility in woman

Answer 1

PCOS

Question 2

What are the life long risks of having PCOS

Answer 2

T2DM
Metabolic syndrome
cardiovascular disease
Endometrial carcinoma

Question 3

What are the different phenotypes for PCOS

Answer 3

Phenotype 1 classic PCOS
oligo anovulation + hyperandrogenism + USS PCO

Phenotype 2 Hyperandrogenic anovulation
oligo anovulation + hyperandrogenism

Phenotype 3 Ovulatory PCOS
Hyperandrogenism + USS PCO

Phenotype 4 Non hyperandrogenic PCOS
oligo anovulation + USS PCO

Question 4

What is the Ferriman Galleway system

Answer 4

different ethnic cut offs Chinese 2-3 abnomral but mediterranian 9-10 abnormal
9 sections scored 1-4 for local areas
Lip, chin, chest, abdomen, pubic hair, back buttocks thigh arms

Question 5

What is the difference between hirtutism and hypertrichosis

Answer 5

Hirsutism - variability expressed manifestation of hyperandrogenism
Idiopathic - non androgen dependent hirsutism does occur
Half of mild hirsutism is not androgenic
Hypertrichosis - not androgen dependent (although can worsen sx) Non sexual pattern
excessive growth vellus hair (can be secondary to drugs)

Question 6

What are the signs of frank virilization

What is the ddx

Answer 6

sx include rapid onset hirsutism, temporal hair recession, increased muscle bulk, voice deepending, clitoromegaly

ddx
Virilizing congential adrenal hyperplasia

Question 7

What is a normal cycle length

Answer 7

Adolescents - 20-89 days are normal