PCO Flashcards
1
Q
PCO roterdam criteria?
A
ANDROGEN EXCESS “chemical, clinical”
ANOVULATION
ADAM’S CRITERIA
4-6 %, most common cause of chronic Anovulation
2
Q
PCO pathology?
A
^ LH… ^Androgen.. adipose… E1
E1… ^LH -FSH
3
Q
Pathology?
A
Ovary.. enlarged
Cyst MSSFF..
Theca and stromal cells hyperplasia
Uterus .. symmetrically enlarged
4
Q
C/P?
A
Anovulation
Oligomenorrhea
Infertility
Acne, hirsutism
5
Q
LONG term complications?
A
Androgen.. ^LDL/HDL .. ISHD
E.. EH..endometriosis.. E Cancer.. fibroid
IR, obesity.. HTM DM2
6
Q
INVESTIGATIONS? Lab
A
LAB.. LH/FSH >2.5 E1/E2 >1 ^PRL ^testosterome, DHEA Decrease progesterone decrease SHBG
7
Q
Investigations? US
A
Adam’s criteria
O follicle > 10cm3
N. >10
Microcyct <10mm
8
Q
TTT? General
A
Weight reduction
Stop smoking
Oral hypoglycemic
9
Q
TTT? Preg.
A
IOO by clomid, GNH Bilat. Laparoscopic ovarian drilling 4-8 in each ovary for 2-4 sec Preg 70% ART
10
Q
TTT? No preg
A
For bleeding COCS for 21 days ... 7 ... repeat Progesterone MPA 10mg/day 16-25 day D&C Hysterectomy
11
Q
TTT? Hirsutism
A
COCS
Diane: 35 mg EE +2mg ceproterone acetate
