IOO&OHSS Flashcards
1
Q
GNRH?
A
Pulsatile.. not practical
Continuous.. pituitary down regulation
NO SE
2
Q
GNH? FSH
A
HMG... FSH:LH 150:75 Urofillitropin 150:1 Recombinant FSH At 3,5,7 +FM GF +18 or E2 1500..1000 LH SURGE
3
Q
LH?
A
HCG urine
HCG genetic
LH
Intercourse within 36 hr
4
Q
SERM? Clomiphine citrate
A
50mg 2/daily at day 5 for 5 days MAX. 4-6 cycles Release of -ve FB on pituitary Increase FSH Stop the drug LH surge
5
Q
GNH DIS?
A
OHSS
Multifeta preg.20
Abortion 15, PTL 15, ectopic 5
Painful injections, expensive
6
Q
SERM DIS?
A
OHSS Multifetal preg. TERATOGENIC as anti E: menopausal $, hostile cx mucous Visual disturbance Breast tenderness GUT upset
7
Q
OHSS
A
HCG injections.. 3-4days
Release of PGS,E,HISTAMINE
IVF …. EVF
8
Q
Pathogenesis of OHSS?
A
IVF… hypovolemia
Hypotension , RF, LF
Hemoconcentration, VTE, DIC
Electrolytes imbalance .. HF
EVF … ascitis, pleural effusion
9
Q
Grade one?
A
Mild.. bilat. Ovarian enlargement
cycts 5x5 cm
E2> 1500 pg/ml
P> 30 pg/ml
10
Q
Grade two?
A
12x12cm
NV,P
Increase weight
11
Q
Sever?
A
All
12
Q
Prophylaxis?
A
Avoid HCG if E2>1500 pg/ml
2 follicles >17 mm
13
Q
TTT?
A
AB, FF,NN antiPGS, analgesics, antihistamine Bed rest Fluid and salt restrictions Follow up No laparotomy except TRH new heparin, albumin
