HyperProlactinemia Flashcards
1
Q
Pathological? 1,2
A
1 hypothalamus •idiopathic. •organic CINT
2 pituitary … adenoma as chromophobe, acidophil > acromegaly, basophil > coushing disease
EARLY Empty sella $
2
Q
Pathological? Hormones
A
Estrogen
Primary hypothyroidism > increased TRH
3
Q
Pathological? Breast
A
Breast disease
Paraneplastic syndrome
4
Q
Pathological? Abdominal
A
Chronic liver disease
Chronic renal disease
5
Q
Pathological? Iatrogenic
A
Anti dopamin?
Anti HTN
Anti emetic
Anti psychotic
6
Q
Physiological?
A
Stress Sleep Sexual intercourse 2nd half of the cycle and pregnancy Surgery Suckling
7
Q
Manifested by?
A
Galactorrhea/ Mastalgia Ovulatory disorder? Amenorrhea Polymenorrhea and spotting (LPD) •HIRSUTISM, •IR CAUSE
8
Q
INVESTIGATIONS?
A
Lab... normal .2 ... 29 ng/ml ...<100... not tumor 100...200 may be tymor ...>200 tumor Image CT brain Endoscopy.. ophthalmoscope Biopsy
9
Q
TTT?
A
Dopamine agonist.. Bromocreptine 2.5mg twice daily ^^SE (NV,HYPOTN) Lisuride .2mg more POTENT, less SE Cabergoline .5 mg twice weekly Quinagolide non ergot
10
Q
TTT of pituitary adenoma?
A
Micro… dopamine agonist
Macro.. trans frontal, trans ethmoidal surgery
Gamma knife
IF GOT PREGNANT CONTINUE ON DOPAMINE AGONIST
