Paxil

Question 1

Another name for Paroxetine

Answer 1

Paxil

Question 2

Paroxetine is known as the _____ SSRI

Answer 2

“calming”

Question 3

Disadvantages of Paroxetine

Answer 3

More: Fatigue, weight gain, sexual dysfunction

Missed dose can cause withdrawals (Short half life)

Anticholinergic effects (Dry mouth, constipation, blurry vision).

Most constipating effect (Paxil packs it in)

Second to Luvox in interactions

Question 4

Why should we avoid prescribing Paxil to anyone pregnant or the elderly?
.”

Answer 4

Increased risk of birth defects and dementia.

Question 5

Population(s) that should not get Paxil

Answer 5

Elderly

Pregnant

Question 6

Paxil is off label for what issue commonly

Answer 6

Premature ejaculation

Question 7

Initial dosing of paxil

Answer 7

20 mg in AM

Question 8

FDA max for paxil

Answer 8

50 mg

Question 9

Paxil is best for this type of patient

Patient’s with these CC(s)

Answer 9

Anxiety + Depression

Insomnia

Question 10

Which formulation is better to use for paxil

Answer 10

The CR

Decreases side effects

Question 11

Therapeutic dosage for Paxil CR

Answer 11

25 mg - 62.5 mg

Question 12

Initial dosage of Paxil CR

Answer 12

25 mg

Question 13

Titration interval for Paxil CR

Answer 13

12.5 mg by weekly

Question 14

Habit forming?

Answer 14

No

Question 15

Common side effect from Paxil

Answer 15

Sedation

Ix: Decrease dosage, take at night time

Question 16

Renal Impairment

Answer 16

Lower Dosage:

Initial - 12.5 mg CR / 10 mg

Maximum - 50 mg CR/ 40 mg

Question 17

Liver Impairment

Answer 17

Lower Dosage:

Initial - 12.5 mg CR / 10 mg

Maximum - 50 mg CR/ 40 mg

Question 18

Cardiac

Answer 18

No issues

Question 19

Elderly

Answer 19

Lower Dosage:

Initial - 12.5 mg CR / 10 mg

Maximum - 50 mg CR/ 40 mg

Try not to start with elderly due to Anticholinergic effects, Risk of dementia & Constipation