patterns and principles of heredity Flashcards
in meiosis a diploid cell produces
4 haploid gametes
the 4 haploid gametes will be..
genetically different
Meiosis 1
reductive division- chromosome number is reduced
Meiosis 2
separation of sister chromatids
Meiosis 1- detail
- division of homologous pairs of chromosomes
- as in mitosis, meiosis is preceded by phase (cells have replicated their DNA)
- Prophase 1- chromosomes condense and homologous pairs form synaptonemal complexes–> cross over occurs
- Metaphase 1- each pair of homologues line up at the equator- centromere doesn’t divide- orientation is random to one another
orientation is random to one another
independent assortment/segregation
synaptonemal complexes
The synaptonemal complex is a protein structure that forms between homologous chromosomes (two pairs of sister chromatids) during meiosis and is thought to mediate chromosome pairing, synapsis, and recombination.
meiosis 2- detail
division of sister chromatids
- Metaphase 2- individual chromosomes line up
- anapase 2- centromeres split and chromatids separate to opp poles
- Telophase 2- each daughter cell contains one chromosome of each type
Gene
specific sequence of DNA which codes for a protein/proteins (alternative splicing)
allele
an alterative form of a gene
genotype
alleles at locus
phenotype
observable characteristics
homozygote
identical (YY) alleles at a locus
particulate theory is associated with
gregor mendel
what is the particulate theory (5)
1) characters are distinct and hereditary determinants (genes) are particulate in nature
2) each adult has two gene for each character- diff forms of the genes are called alleles
3) members of the gene pair and segregate equally into gametes
4) fusion of the gametes at fertilisation restores the pair of genes and is RANDOM
5) different genes assort independently in gametes
fusion of gametes and therefor the restoration of the pair of genes is..
RANDOM
meiosis results in the formation of two types of gametes..
in equal numbers
fertilisation..
restores the two copies of the gene to the offspring
if both parents are heterozygous
3 different genotypes and 2 phenotypes
independent assortment
When homologous chromosomes, one from each parent, pair up along the equator during metaphase 1 of meiosis, the particular arrangement is determined by chance.
- increases variation within populations
when does independent assortment occur
metaphase 1
what occurs in metaphase 1
independent assortment
probability applied to hybrid crosses
-two alleles possible (from each parent) and each gamete can only carry one allele, therefore what is the probability of either gamete is..
1/2
therefore if two heterozygous parents are crossed
genotypic ratio is 1:2:1
phenotypic ratio is 3:1
therefore if two heterozygous parents are crossed: probability of (YY)
p(Y gamete) from parent 1 and p(Gamete) from parent 2=
1/2 x 1/2 =1/4
therefore if two heterozygous parents are crossed: probability of (Yy)
p(Y gamete) parent 1 and p(y gamete) from parent 2 =
(1/2 x 1/2) + (1/2 x 1/2) = 1/4 + 1/4 = 1/2
in dihybrid crosses one must
consider each trait independently
if two traits are independent normal ratio is
9: 3:3:1
- ration is a random combination of two independent 3:1 ratios