hardy weinberg and fittness Flashcards

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1
Q

hardy winbergy equation

A

p2+ 2pq + q2 =1

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2
Q

p+ q=

A

1

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3
Q

p=

A

frequency of one allele in the pop. ( dominant)

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4
Q

q=

A

frequency of other alleles (recessive)

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5
Q

p2=

A

proportion of population that is homozygous for the first alleles (RR)

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6
Q

2pq

A

proportion of the population that is heterozygous ( Rr)

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7
Q

q2

A

proportion of the population txt is homozygous for the second allele (rr)

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8
Q

H-W equilibrium only applies when

A

1) discrete generations
2) allele frequency is the same in each sex
3) mendelian segregation occurs
4) population size is large so no genetic drift
5) no gene flow (imm/em)
6) no mutation
7) mating occurs at random
8) no selection

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9
Q

in the case of dominant and recessive alleles

A

you can easily count the number of individuals with the recessive phenotype

  • this will give ou the frequency of the double recessive genotype - q2 or dominant (p2.
  • with that value you can go on and calc. the frequencies of all other genotypes and alleles
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10
Q

large population so no genetic drift

A
  • genetic drift affects small populations

- genetic drift reduced genetic variation

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11
Q

no migration or gene flow

A

migration transfers individuals amongst population

  • gene flow transfers alleles amongst population
  • can either increase or decrease genetic variation
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12
Q

no mutation

A
  • increase genetic variation
  • some mutations create dominant alleles, some create recessive or co-dominant alleles
  • mutations may be be harmful, neutral or favourable
  • effect depends on environment
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13
Q

mating occurs at random

A
  • non random mating does not change allele frequencies, but rather hcnages how the alleles are distributed into diploid genotypes
  • commone maple of non random mating includes assertive and dissortative mating and inbreeding
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14
Q

assortative mating

A

when individuals mate with those that are similar to themselves - non random
–> leads to an increase in homozygotes

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15
Q

disassortative mating

A

breeding between individuals with dissimilar genotypes- more rare
–> increase in heterozygotes

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16
Q

H-W is

A

of limited use due to fe organisms fulfilling all of these rules

17
Q

Hardy weingberg provides a way of testing whether

A

a population has evolved or not

-if assumptions are not met the population will evolve

18
Q

if the assumptions are not met a population….

A

will evolve

19
Q

fitness is used to

A

measure reproductive success

20
Q

components of fitness

A
  1. survivorship

2. fecundity

21
Q

where is fineness manifested within

A

phenotype

22
Q

what is phenotype affected by

A

genes and environment

23
Q

why may fitness of different individuals with the same genotype be different in diff environments

A

the fitness of a given phenotype can be diff in diff environments
e.g. polar bears white coat acts as camouflage in the north pole and would provide fitness. However if a polar bear was in the jungle its white coat would decrease its fitness

24
Q

(W)

A

fitness

25
Q

definition of fitness

A

W is defined as the reproductive success of a genotype relative to the optimum genotype

26
Q

Fitness =

A

W=1-s

27
Q

s

A

selection

28
Q

what will be affected if certain alleles affect fitness

A

the frequency of the alleles will change over time

  • alleles with higher fitness become more common–> natural selection
29
Q

alleles with higher fitness will

A

become more common –> NS

30
Q

methods of measuring fitness

A
  • measure relative survival of the genotypes within a generation. Kettle well;s mark-recapture experiment with he peppered moth is an example.
  • measure changes in gene frequencies between generation; we then substitute the measurements in the formula that expresses fitness in terms of gene frequencies in successive generations
  • measure deviation from H-W ratios- this is used in estimating fitness in the case off sickle cell anaemia
31
Q

what is measuring deviation from H-W ration used in

A

measuring fitness in the case of sickle cell anaemia