hardy weinberg and fittness Flashcards
hardy winbergy equation
p2+ 2pq + q2 =1
p+ q=
1
p=
frequency of one allele in the pop. ( dominant)
q=
frequency of other alleles (recessive)
p2=
proportion of population that is homozygous for the first alleles (RR)
2pq
proportion of the population that is heterozygous ( Rr)
q2
proportion of the population txt is homozygous for the second allele (rr)
H-W equilibrium only applies when
1) discrete generations
2) allele frequency is the same in each sex
3) mendelian segregation occurs
4) population size is large so no genetic drift
5) no gene flow (imm/em)
6) no mutation
7) mating occurs at random
8) no selection
in the case of dominant and recessive alleles
you can easily count the number of individuals with the recessive phenotype
- this will give ou the frequency of the double recessive genotype - q2 or dominant (p2.
- with that value you can go on and calc. the frequencies of all other genotypes and alleles
large population so no genetic drift
- genetic drift affects small populations
- genetic drift reduced genetic variation
no migration or gene flow
migration transfers individuals amongst population
- gene flow transfers alleles amongst population
- can either increase or decrease genetic variation
no mutation
- increase genetic variation
- some mutations create dominant alleles, some create recessive or co-dominant alleles
- mutations may be be harmful, neutral or favourable
- effect depends on environment
mating occurs at random
- non random mating does not change allele frequencies, but rather hcnages how the alleles are distributed into diploid genotypes
- commone maple of non random mating includes assertive and dissortative mating and inbreeding
assortative mating
when individuals mate with those that are similar to themselves - non random
–> leads to an increase in homozygotes
disassortative mating
breeding between individuals with dissimilar genotypes- more rare
–> increase in heterozygotes