Pathophysiology of Intestinal Obstruction in the Horse (Mudge) Flashcards
Take me from the esophagus to anus – what is the order of the equine digestive tract?
- Esophagus
- Stomach (cranial left side)
- Duodenum (right -> left)
- Jejunum (70ft long)
- Ileum
- Cecum (right side)
- Right ventral colon
- Sternal flexure
- Left ventral colon
- Pelvic flexure
- Left dorsal colon
- Diaphragmatic flexure
- Right dorsal colon
- Transverse colon
- Descending (small) colon
- Rectum
- Anus
What is colic?
- Refers to abdominal pain
- Usually involves the disorders of the gastrointestinal system
How many feet of small intestine does the average adult horse have?
70ft
Classification of Obstruction:
Includes simple and strangulating
- Luminal obstruction causes accumulation of solid, liquid, and gas
- Acute onset of clinical signs
Complete
Classification of Obstruction:
Usually simple obstruction
- Luminal obstruction causes accumulation of solid +/- liquid
- Often liquids and gas ‘squeak’ past the obstruction
- Slower onset of signs of an obstruction than complete
Incomplete
Simple Obstructions:
- Stricture
- Intraluminal
- Intraluminal Obstruction
- Impaction (feed or sand)
- Enterolith
- Mass (neoplasia or FB)
- Extraluminal
Mechanical
Simple Obstructions:
- Visceral displacements
Malposition
- “large colon”
Simple Obstructions:
- Ileus
- Inflammation (enteritis)
Functional
- not a true obstruction
Simple intestinal obstruction can lead to increased intraluminal pressure. What are 3 secondary intestinal effects that can occur after simple obstruction?
- Decreased perfusion to seromuscular and mucosal layers
- Increased microvascular permeability
- Mesothelial cell loss, neutrophil infiltration, edema – can lead to adhesion formation
- Can also lead to pressure necrosis, especially with a solid obstruction (enterolith)
Definition:
an abnormal union of membranous surfaces due to inflammation or injury.
Adhesion
List simple obstructions in the small intestine:
- Impaction
- Ileal impaction
- Ascarids
- Foreign body (rare)
- Mass/ neoplasia (not very common)
- Adhesions
- Intussusception
- initially non-strangulating
- Functional
- ileus
- enteritis
List simple obstructions – Large Intestinal Impaction/Obstruction:
- Feed impaction
- Pelvic Flexure
- Right dorsal colon/ Transverse colon
- Cecum (less common)
- Type I = feed
- Type II = functional/fluid
- Small colon
- Often inflammatory
- Narrowing of the intestinal lumen
List other simple obstructions – Large Intestinal Impaction/Obstruction:
- Sand Impaction
- RDC
- Enterolith
- RDC
- Transverse & Small Colon
- Fecalith
- Small Colon - Minis and foals
- Phytotrichobezoars (eating hair)
List the Risk Factors for simple Obstructions:
- Ileal Impaction
- Jejunal Impaction
- Ileocecal, cecoceal, cecocolic intussusception
- Large colon impactions (stress, diet, dentition, dehydration)
- Large colon displacement (recent dietary changes, recent parturition, large breed)
- Enterolithiasis (alfalfa hay, breed (Arabian, Miniature), lack of pasture access, geography)
What are enteroliths made of?
(enteroliths are made of magnesium, ammonium, phosphate)
Struvite