Pathophysiology Flashcards
1
Q
Incidence rate of HF
A
2% of population in Europe
Most common hospitalisation for over 65yrs
2
Q
Most common cause of HF?
A
CAD then Hypertension
3
Q
5yr mortality after first HF event
A
50%
4
Q
Causes of death in HF for NYHA II
A
Mainly sudden death
5
Q
Causes of death in HF for NYHA VI
A
Mainly pump failure
6
Q
Is CRT better for systolic or diastolic HF
A
Systolic with low EF
7
Q
Vicious cycle of HF?
A
1 CO and BP lower
2 RAAS activation
3 HR, Contractility and Vasoconstriction increase
4 Sodium retention
5 Blood volume, CO and BP increase
6 Preload, Afterload and workload increase
8
Q
First line drugs for HF
A
Beta blockers
Ace inhibitors
Diuretics
9
Q
What percentage of HF patients have broad QRS
A
25%
10
Q
What percentage of CRT patients don’t respond
A
20-30%
