CRT Trials and indications

Question 1

The 3 early trials

Answer 1

PATH CHF
MUSTIC
MIRACLE

Question 2

Which of the 3 early trials looked at NYHA III

Answer 2

Mustic

Question 3

Which of the 3 early trials looked at epicardial leads

Answer 3

PATH CHF

Question 4

The mid 2 trials looking at NHYA III - IV

Answer 4

CARE HF

COMPANION

Question 5

What did companion show

Answer 5

ICD/PPM CRT is better than OPT MEDICAL by 40%

Question 6

What were the 3 trials for mild HF NYHA II

Answer 6

REVERSE
MADIT CRT
RAFT

Question 7

What did reverse show

Answer 7

CRT on is better than off in mild symptom patients

Question 8

What did MADIT CRT show

Answer 8

CRT is better than ICD

LBBB patients do better than without LBBB patients

Question 9

What did RAFT show

Answer 9

CRTD is better than ICD

Question 10

Two studies looking at narrow QRS

Answer 10

ReTHINQ
Echo - CRT

Showed patients didn’t fare better / worse

Question 11

NYHA III / VI indications

Answer 11

1 - Symptomatic
2 - Best medical therapy
3 - LVEF < 35%
4 - QRS > 120ms 
5 - SR

1A level

Question 12

NYHA II

Answer 12

1 - Symptomatic
2 - Best medical therapy
3 - QRS > 150ms
4 - SR

1A level

Question 13

Males or females do better with CRT?

Answer 13

Females

Question 14

What did Madit CRT show with regard to pacing percentages?

Answer 14

> 97% did best

Question 15

Which Study accepted AF and SR

Answer 15

Mustic

Question 16

Which studies looked at CRT in conventional Pacing indicated patients

Answer 16

Block HF / BioPace

Question 17

What did Block HF show?

Answer 17

CRT marginally better than RV pacing

Question 18

What did Biopace show

Answer 18

CRT marginally better than RV pacing