Pathophys and Anatomy Flashcards
What is the pathophys of denervation?
hypersensitivity to acetylcholine acting at the denervated NMJ
Horner Syndrome
injury to the sympathetic supply to the eye
Anhidrosis is seen from interruption of fibers that run along the __ artery.
external carotid
Blockage at what anatomical landmark may lead to non-obstructive hydrocephalus?
aqueduct of Sylvius
What type of tumor is more likely to arise from the tentorium cerebelli?
meningioma because it is a fold of meninges
What wave activity is expected in a relaxed man/woman?
alpha wave - frequency of 8-13 Hz
What anatomical feature does the ulnar nerve traverse in the elbow?
ulnar groove –> under aponeurosis of flexor carpi ulnaris in the cubital tunnel
The __ nerve supplies the biceps brachii, brachialis, coracobrachialis muscles.
musculocutaneous
also carries sensory information
___ in neonates is fragile and at increased risk of rupture, leading to intraventricular hemorrhage.
germinal matrix blood vessels
What is the pathogenesis of NPH?
increase in ICP –> ventricular enlargement
from diminished CSF absorption at arachnoid villi
What deficiency is associated with Niemann-Pick disease?
Sphingomyelinase deficiency
What deficiency is associated with Tay Sachs disease?
beta-hexosaminidase A deficiency
What portion of the spinal cord is affected in Friedreich ataxia?
dorsal columns, dorsal root ganglia, spinocerebellar tracks, lateral cortocospinal tract
Why is limb coordination spared in cerebellar degeneration due to alcohol neurotoxicity?
degeneration is mostly Pukinje cells in the cerebellar vermis - more effects on truncal coordination
What are the three dopamine pathways targeted by antipsychotic medications?
mesolimbic
nigrostriatal
tuberoinfundibular
