Pathology review Flashcards
Pathology
the study of disease in which the 1st concern is the etiology and the second is pathogenesis
etiology
cause of disease
pathogenesis
how a disease develops
What has the scientific community developed to look at what causes disease?
Koch’s postulates- follows the germ theory of disease
What are Koch’s postulates?
- The microbe must be isolated from ALL individuals with the given disease
- the microbe must be grown as a pure culture
- inoculation of the microbe into a healthy individual should cause the SAME disease symptoms
- The SAME organism must be isolated from the newly inoculated individual
Where do Koch’s postulates work?
Helicobacetr pylori- bacteria causes gastric ulcers and gastric cancer
Mycobacterium tuberculosis- causes TB
Bacillius anthracis- causes anthrax
What are exceptions to Koch’s postulates?
HIV VIRUS: ; only infects humans cannot infect humans with virus that is infectious
Treponema pallidum- bacteria
syphilis- hard to grow and isolate
hard to get a pure culture
Disease
noticeable impairment of the body function
1. symptoms and signs
symptoms
what the patient feels
- pain malaise
- subjective and can change
sign
objective and concrete
can be measured though a direct observation
communicable
this is a disease which is spread from one individual to another through either direct or indirect contact
ex- gonorrhea COVID FLU
contagious
easily spread
ex- chicken pox covid
non communicable
not spread from person to person
ex- tetanus
endemic
low and constant levels of the disease in a given population
ex- malaria and HIV
epidemic
high numbers of infected people in a given area
short duration
ex- chicken pox in schools