Pathology of Gastric Diseases Flashcards
1
Q
What makes up the protective barrier of the stomach lining?
A
- Mucus Secretion
- Bicarbonate secretion
- Epithelial barrier with tight junctions
- Prostaglandin synthesis
2
Q
Complications of H. pylori chronic gastritis
A
- Peptic ulcer (duodenal ulcers and 70% of gastric ulcers)
- gastric atrophy and intestinal metaplasia
- gastric dysplasia (premalignant stage)
- gastric carcinoma
- gastric lymphoma (MALT lymphoma)
3
Q
What is this lesion?
A
Benign gastric ulcer
4
Q
What are the complications of benign duodenal ulcers?
A
- Bleeding (may be life-threatening)
- Perforation (leading to peritonitis)
- outflow obstruction (intractable nausea and vomiting)
5
Q
What are the characteristics of autoimmune gastritis?
A
- antibody mediated destruction of parietal cells
- associated with pernisious anemia (B12 deficient)
- gastric atrophy and intestinal metaplasia
- endocrine cell hyperplasia
