Approach to diarrhea Flashcards
function of the small intestine and properties helping its function
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anatomical consideration of large intestine
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describe the physiology of stool water balance
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functional design of small intestine
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describe physiology of fluid and electrolyte transport
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principles of water transport
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electrolyte transport
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paracellular pathway
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how solutes cross membranes
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absorption - pump
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nutrient coupled absor[tion of sodium
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secretion - chloride
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heterogeneity along the crypt villus axis
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regulation
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function of second messengers
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overview of mechanisms of diarrhea
- osmotic
- secretory
- inflammatory
- dysmotility
osmotic diarrhea - mechanism and archetype
Mechanism:
Archetype
clinical and laboratory hallmarks of osmotic diarrhea
- stops with fasting
- increase in stool osmotic gap***
Causes of osmotic diarrhea
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Secretory diarrhea - mechanism and archetype
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How does vibrio work? And why does oral rehydration solution work?
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Clinical and laboratory hallmarks of secretory diarrhea?
- fasting has no effect
- no increase in stool osmotic gap
Other causes of secretory dirrhea
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Lubiprostone - function and effectiveness
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Inflammatory diarrhea
mechanism
archetype
clinical/laboratory hallmakrs of inflammatory diarrgea and other examples
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Dysmotility type - mechanism and archetype
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Dysmotility type - dumping syndrome
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Clinical and laboratory hallmarks of dysmotility type
.