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Year 2 Respiratory > Pathology of chest malignancies > Flashcards

Pathology of chest malignancies Flashcards

1
Q

what is the most common malignant lesion in the chest?

A

metastasis

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2
Q

what are the most common benign lesions in the chest?

A

granulomas

chronic pneumonia and abscess

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3
Q

which type of cancer makes up the vast majority of lung neoplasms?

A

carcinoma

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4
Q

what are the top 4 causes of pleural exudate?

A

microbes
cancer
pulmonary infarction
viral pleuritis

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5
Q

what are the diagnostic methods for diagnosing lung cancer?

A

sputum cytology
FNA
biopsy

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6
Q

hypercalcemia is more typically seen with what cancer type? the majority of the other paraneoplastic syndromes are seen with what type?

A

squamous cell CA

small cell

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7
Q

pancoast tumor is usually due to what cancer type?

A

squamous (can be adenoCA)

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8
Q

what are the histological classifications of lung tumors?

A

adenocarcinoma
squamous cell CA
small cell CA
large cell CA

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9
Q

what are the clinical classifications of lung tumors? what are they based on?

A

non small cell CAs
small cell CAs
combined patterns

response to chemo and likelihood of metastases

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10
Q

what are the mutations seen in adenocarcinomas?

A

KRAS and EGFR

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11
Q

KRAS and EGFR mutations are seen in what type of lung cancer?

A

adenocarcinoma

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12
Q

what are the two forms of adenocarcinoma?

A

bronchial

bronchioalveolar

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13
Q

what is the origin of bronchoalveolar CA?

A

bronchoalveolar stem cells

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14
Q

which lung cancer produces keratin?

A

squamous

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15
Q

which syndromes can result from squamous cell CA?

A

SVC

pancoast

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16
Q

what is the treatment of choice for SCLC?

A

chemo

17
Q

which lung cancer is considered undifferentiated?

A

large cell CA

18
Q

what is the most common metastasis site for primary lung cancer?

A

lymph nodes

19
Q

what are tumorlets?

A

benign, small clusters of hyperplastic neuroendocrine cells

20
Q

what is the benign pleural tumor?

A

pleural fibroma

21
Q

what is the malignant pleural tumor?

A

mesothelioma

22
Q

spindle cell tumor

A

solitary fibrous tumor (pleural fibroma)

Year 2 Respiratory (34 decks)

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