pathology mid term Flashcards

1
Q

pathology def:

A

the study of diseases

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2
Q

actiology def

A

causes/reason for disease

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3
Q

diff types of actiology

(3)

A
  • predisposing factors
  • exciting factor
  • pathogenesis
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4
Q

predisposing factors def

A

factors that help the development of the disease

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5
Q

exciting factor def

A

direct cause of the disease

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6
Q

pathogenesis def

A

basically how the causitive agent produces changes in the tissues

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7
Q

pathological pic types

(2)

A
  • gross (macroscopic)
  • microscopic (histopathology)
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8
Q

gross picture def

A

changes in tissue detected by the naked eye

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9
Q

fate def

A

end result of the disease (either cured or death)

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9
Q

microscopic pic def

A

changes in tissue deteceted on microscopic examination

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10
Q

complications def

A

additional pathological changes during or after the termination of the usual course of the disease

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11
Q

inflammation def

A

local vascular, lymphatic & cellular reactions of living tissue againts an irritant

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12
Q

causes of inflammation

(3)

A
  • living irritants
  • non living irritants
  • antigens
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13
Q

what are living irritants

A

bacteria, viruses, parasites etc

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14
Q

non living irritants include:

(3)

A
  • physical: excess heat & cold
  • chemical: acids, alkalies, poisons etc
  • mechanical: trauma, mechanical friction etc
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15
Q

antigens def

A

cause allergic inflammation

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16
Q

accute inflammation def

(4)

A
  • short duration (days-weeks)
  • rapid response
  • sudden onset
  • fluid exudate
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17
Q

chronic inflammation def

(4)

A
  • prolonged action (months-years)
  • slow response
  • gradual onset
  • macrophages, plasma, lymphocytes etc
18
Q

chemotaxis def

A

directed movement of polymorphonuclear leucocytes & macrophaes in the area of inflammation towards the irritant

19
Q

phagocytosis

A

ingestion & destruction of bacteria & foreign bodies by microphages

20
Q

signs & symptoms of acute inflammation:

(5)

A
  • redness
  • hotness
  • swelling
  • pain
  • loss of function
21
Q

types of acute inflammation:

(2)

A
  • suppurative
  • non suppurative
22
Q

non suppurative types:

(8)

A
  • catarrhal
  • membranous
  • sero-fibrinous
  • fibrinous
  • serous
  • haemorrhagic
  • necrotizing
  • allergic
22
Q

composition of pus

(4)

A
  • bacteria
  • liquefied necrotic tissue
  • inflammatory cellular exudate
  • inflammatory fluid exudate
23
suppurative inflammation types: | (2)
- localized - abscess - furuncle - carbuncle - diffuse
24
abscess def
**localized suppurative** **inflammation** resulting in the formation of an **irregular cavity containing pus**
25
furuncle def
small abscess related to a hair follicle
26
carbuncle def
type of localized suppuration
27
cellulitis | (def & cause)
- def: acute diffuse suppurative inflammation - cause: streptococcus haemolyticus
28
types of chronic inflammation
- specific - non specific
29
granulomas def
a type of **chronic specific inflammation** which accumulates a large number of macrophages together with lymphocytes etc **to form tumour like masses**
30
infective granuloma types | (3)
- bacterial - parasitic - fungal
31
repair def:
replacement of damaged tissue by new healthy one
31
non infective types
- silicosis & asbestosis
32
types of repair: | 2
- regeneration - healing by fibrosis
33
regeneration def
replacing damaged cells by new cells of same kind
34
repair in nervous system
IT DOES NOT OCCCUR IN THE BRAIN & SPINAL CORD (dead cells removed through gliosos)
35
complications of wound healing: | (7) IMPORTANT
- chronic ulcer - sinus - fistula - keloid - contraction - implantation cyst - squamos cell carcinoma
36
causes of cell injury | (7) IMPORTANT
- hypoxia - infectious agents - physical agents - chemical agents - immunological reactions - nutritional deficiences - genetic & enzymatic derangements
37
diff between reversible & irreversible cell injury
- mild vs severe - short vs long duration - irreversible has damage to nucleus & cell death
38
necrosis def
local death of cells in living body
39
types of necrosis: | (4)
- coagulative - liquefactive - caseation - fat
40
apoptosis def
programmed cell death
41
apoptosis occurence: | (4)
- normal cell turnover - during embryonic dev - endocrine - patho conditions - radiation - death by cytotoxic - liver cells - reduction of cell number