Pathology - Male Flashcards

1
Q

Abnormal opening on the ventral aspect on the penis

A

Hypospadias

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2
Q

Abnormal opening on the dorsal aspect of the penis

A

Epispadias

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3
Q

Local inflammation of the glans penis

A

Balanitis

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4
Q

Inflammation of the overlying prepuce

A

Balanoposthitis

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5
Q

prepuce cannot be retracted easily

A

phimosis

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6
Q

Penile neoplasms usually

A

squamous (uncircimsized) > 40y/o, can spread to inguinal lymph node (poor prognosis)

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7
Q

Carcinoma in situ of penis; a/w HPV - gray, crusty plaques on the penis

A

Bowen disease

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8
Q

Red velvety plaques on the penis a/w HPV

A

Erythroplasia of Queyrat

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9
Q

small flesh colored patches on the penis, pre-malignant (2-3%), many regress

A

Bowenoid Papulosis

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10
Q

most common cause of scrotal enlargement (serous fluid w/in the tunica vaginalis)-> transluminesence

A

hydrocele

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11
Q

Failure of testicular descent

A

Cryptorchidism

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12
Q

Post-pubertal male tumors?

A

germ cells 95% (all malignant)

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13
Q

mutation in germ cell tumors in males?

A

i(12p)

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14
Q

Female analogy to seminoma

A

Ovarian dysgerminoma

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15
Q

Large cells, distinct border, rare lymphocytes

A

seminoma

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16
Q

Older pt, no a/w intratubular germ cell neoplasia, polygonal cells of variable size organized in nodules/ sheets

A

spermatocyte seminoma

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17
Q

most common testicular neoplasm in young boys, good prognosis; a/w embryonic cacrinoma in adults

A

yolk sac tumor

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18
Q

buzz pathology word for yolk sac tumor

A

Schiller-Duvall bodies

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19
Q

tumor markers (2) for yolk sac

A

anti-trypsin &AFP

20
Q

indistinct boder, ill-defined, hemorrhage & necrosis testicular carcinoma

A

embyronic carcinoma

21
Q

testicular carcinoma - pleuripotent; diff. along trophoblastic lines; increase in HCG, poor prognsosis
hemorrhage & necrosis

A

choriocarcinoma

22
Q

neoplastic germ cells diff. along somatic lines (mostly in combo w/ other cell types)
(pre-puberty = benign)
(post-puberty = malignant)

A

Teratoma

23
Q

tx for bacterial prostitis

A

Trimethoprim/sulfa or cipro (Rx delivery)

24
Q

Cause of granulomatous prostitis due to?

A

BCG instillation in bladder for tx of superficial bladder cx

25
Q

Benign Prostate Hyperplasia (BPH)

A

stromal & epithelial elements, excessive androgen (DHT) growth; hyperplastic gland

26
Q

BPH, hyperplastic glands, inner columnar, outer flat squamous, secrete proteinaceous…

A

corpora amylacea

27
Q

RX that blocks DHT formation

A

Finestride

28
Q

Rx that blocks adrenergic receptors for BPH

A

Flomax

29
Q

Prostate cx is graded by?

A

Gleason system

30
Q

pouch-like evagination mostly due to urethral obstruction

A

bladder diverticulum

31
Q

Can result in transmural fibrosis –> painful contracted bladder

A

Intersitial cystitis

32
Q

phagosomes become overloaded, enlarged lysosomes

A

Malakoplakia - Michaelis Gutmann bodies

33
Q

Bladder cx presentation

A

painless hematuria

34
Q

A/w squamous bladder cx

A

urinary Schistomiasis

35
Q

tertial syphilis, necrotic tissue in bone, skin, mucous membranes, upper airway

A

gumma

36
Q

Congential Syphilis, Huthison Triad

A

1- notched incisors
2- intersitial keratitis w/ blindness
3- deafness (8th CN)

37
Q

Chronic ulcerative disease caused by Chylamdia, mixed granulomatous, neutrophilic inflammatory response
Steleate abscesses in lymph nodes increase lymphedema

A

LGV= lymphogranuolma venereum

38
Q

Most common cause of ulcers in Africa & Asia/ painful; Haemophilius

A

Chancroid

39
Q

Protozoa that may increase pH by decreasing acid producing Duderlein bacili

A

Trichomonas

40
Q

Neonatal HSV fatal b/c a/w

A

rash, encephilits, pneumonitis, hepatic necrosis

41
Q

HPV complications in neonate

A

papillomas in upper respiratory tract

42
Q

Another name for yolk sac tumor

A

Endodermal sinus

43
Q

Nearly always malignant in men and equivalent of a dermatoid cyst in women is nearly always benign

A

Mature teratoma

44
Q

non-germ cell tumor from testicular stroma; intracytoplasmic Reinke crystals
can cause precocious puberty in children or gynecomastia in adults

A

Leydig tumor

45
Q

Increase in free PSA a/w?

A

BPH

46
Q

Increase in bound alpha-antichymotrypsin

A

prostate cx

47
Q

Donovan bodies a/w?

A
Granuloma inguinale 
Calymmatobacterium granulomatis (gram neg rod)