Pathology - Male

Question 1

Abnormal opening on the ventral aspect on the penis

Answer 1

Hypospadias

Question 2

Abnormal opening on the dorsal aspect of the penis

Answer 2

Epispadias

Question 3

Local inflammation of the glans penis

Answer 3

Balanitis

Question 4

Inflammation of the overlying prepuce

Answer 4

Balanoposthitis

Question 5

prepuce cannot be retracted easily

Answer 5

phimosis

Question 6

Penile neoplasms usually

Answer 6

squamous (uncircimsized) > 40y/o, can spread to inguinal lymph node (poor prognosis)

Question 7

Carcinoma in situ of penis; a/w HPV - gray, crusty plaques on the penis

Answer 7

Bowen disease

Question 8

Red velvety plaques on the penis a/w HPV

Answer 8

Erythroplasia of Queyrat

Question 9

small flesh colored patches on the penis, pre-malignant (2-3%), many regress

Answer 9

Bowenoid Papulosis

Question 10

most common cause of scrotal enlargement (serous fluid w/in the tunica vaginalis)-> transluminesence

Answer 10

hydrocele

Question 11

Failure of testicular descent

Answer 11

Cryptorchidism

Question 12

Post-pubertal male tumors?

Answer 12

germ cells 95% (all malignant)

Question 13

mutation in germ cell tumors in males?

Answer 13

i(12p)

Question 14

Female analogy to seminoma

Answer 14

Ovarian dysgerminoma

Question 15

Large cells, distinct border, rare lymphocytes

Answer 15

seminoma

Question 16

Older pt, no a/w intratubular germ cell neoplasia, polygonal cells of variable size organized in nodules/ sheets

Answer 16

spermatocyte seminoma

Question 17

most common testicular neoplasm in young boys, good prognosis; a/w embryonic cacrinoma in adults

Answer 17

yolk sac tumor

Question 18

buzz pathology word for yolk sac tumor

Answer 18

Schiller-Duvall bodies

Question 19

tumor markers (2) for yolk sac

Answer 19

anti-trypsin &AFP

Question 20

indistinct boder, ill-defined, hemorrhage & necrosis testicular carcinoma

Answer 20

embyronic carcinoma

Question 21

testicular carcinoma - pleuripotent; diff. along trophoblastic lines; increase in HCG, poor prognsosis
hemorrhage & necrosis

Answer 21

choriocarcinoma

Question 22

neoplastic germ cells diff. along somatic lines (mostly in combo w/ other cell types)
(pre-puberty = benign)
(post-puberty = malignant)

Answer 22

Teratoma

Question 23

tx for bacterial prostitis

Answer 23

Trimethoprim/sulfa or cipro (Rx delivery)

Question 24

Cause of granulomatous prostitis due to?

Answer 24

BCG instillation in bladder for tx of superficial bladder cx

Question 25

Benign Prostate Hyperplasia (BPH)

Answer 25

stromal & epithelial elements, excessive androgen (DHT) growth; hyperplastic gland

Question 26

BPH, hyperplastic glands, inner columnar, outer flat squamous, secrete proteinaceous...

Answer 26

corpora amylacea

Question 27

RX that blocks DHT formation

Answer 27

Finestride

Question 28

Rx that blocks adrenergic receptors for BPH

Answer 28

Flomax

Question 29

Prostate cx is graded by?

Answer 29

Gleason system

Question 30

pouch-like evagination mostly due to urethral obstruction

Answer 30

bladder diverticulum

Question 31

Can result in transmural fibrosis --> painful contracted bladder

Answer 31

Intersitial cystitis

Question 32

phagosomes become overloaded, enlarged lysosomes

Answer 32

Malakoplakia - Michaelis Gutmann bodies

Question 33

Bladder cx presentation

Answer 33

painless hematuria

Question 34

A/w squamous bladder cx

Answer 34

urinary Schistomiasis

Question 35

tertial syphilis, necrotic tissue in bone, skin, mucous membranes, upper airway

Answer 35

gumma

Question 36

Congential Syphilis, Huthison Triad

Answer 36

1- notched incisors 2- intersitial keratitis w/ blindness 3- deafness (8th CN)

Question 37

Chronic ulcerative disease caused by Chylamdia, mixed granulomatous, neutrophilic inflammatory response Steleate abscesses in lymph nodes increase lymphedema

Answer 37

LGV= lymphogranuolma venereum

Question 38

Most common cause of ulcers in Africa & Asia/ painful; Haemophilius

Answer 38

Chancroid

Question 39

Protozoa that may increase pH by decreasing acid producing Duderlein bacili

Answer 39

Trichomonas

Question 40

Neonatal HSV fatal b/c a/w

Answer 40

rash, encephilits, pneumonitis, hepatic necrosis

Question 41

HPV complications in neonate

Answer 41

papillomas in upper respiratory tract

Question 42

Another name for yolk sac tumor

Answer 42

Endodermal sinus

Question 43

Nearly always malignant in men and equivalent of a dermatoid cyst in women is nearly always benign

Answer 43

Mature teratoma

Question 44

non-germ cell tumor from testicular stroma; intracytoplasmic Reinke crystals can cause precocious puberty in children or gynecomastia in adults

Answer 44

Leydig tumor

Question 45

Increase in free PSA a/w?

Answer 45

BPH

Question 46

Increase in bound alpha-antichymotrypsin

Answer 46

prostate cx

Question 47

Donovan bodies a/w?

Answer 47

``` Granuloma inguinale Calymmatobacterium granulomatis (gram neg rod) ```