Pathology: HIS

Question 1

Normal RBC

Answer 1

Size equal to Nucleus of lymphocyte

Question 2

Small, Medium, Large

Answer 2

Small: 1-2 RBC size
Medium: 3-4 RBC size
Large: >=3 RBC size

Question 3

Lymphocyte

Answer 3

Small
Moderately high N/C ratio
Roundish nuclei
Chromatin staining pattern: clumped
Mature cell should not have prominent nucleoli
No granules
Lightly basophilic cytoplasm
Smooth cytoplasmic border

Question 4

Immature cells

Answer 4

1. Medium - Large size
2. Prominent nucleoli
3. Irregular nuclei
4. Fine chromatin pattern (less dense)
5. High N/C ratio
   —> Blast

Question 5

***Abnormal Promyelocyte

Answer 5

1. Bilobed nuclei
2. Abundant granules
3. Auer rods