Pathology (Cellular Injury)

Question 1

Bacteria responsible for gangrenous necrosis

Answer 1

Clostridium,, streptococcus

Question 2

Why gangrene is black

Answer 2

Iron sulphide from hemoglobin degradation

Question 3

Gas gangrene forms bacteria

Answer 3

Clostridium perfringens

Question 4

What type of necrosis is associated with malignant hypertension

Answer 4

Fibrinogen necrosis

Question 5

Mediators of apoptosis

Answer 5

p53 (checks genome)
bcl-2 (inhibitor)
fas(CD 95)-protease activator
Caspases (lead)

Question 6

What phagocytoses apoptotic cells

Answer 6

Neighboring cells

Question 7

What phagocytoses necrotic cells

Answer 7

Neutrophils, macrophages

Question 8

Type of cell death in HIV

Answer 8

Apoptosis

Question 9

Relation between apoptosis and autoimmune disease

Answer 9

Decreased apoptosis

Question 10

Composition of granulation tissue

Answer 10

Capillary and myofibroblast

Question 11

Secretion of Fibroblast

Answer 11

Collagen, matrix components

Question 12

Excess granular tissue protruding above wound surface is called

Answer 12

Proud flesh

Question 13

Keloid is common in which ethnic group

Answer 13

Africans

Question 14

Relaxed skin tension is similar to what

Answer 14

Langer’s line

Question 15

Steps of reconstructive ladder

Answer 15

Primary closure
Delayed primary closure
Split thickness skin graft
Full thickness skin graft
Local/random pattern flap
Regional/pedicled flap
Free flap

Question 16

Why bradycardia in inferior MI

Answer 16

SA node is supplied by right coronary artery, so ischemia here will cause it