Pathology associations

Question 1

What murmur do you find in: ASD

Answer 1

split S2 due to delayed closure of pulmonic valve

Question 2

What murmur do you find in: PDA

Answer 2

holosystolic machine like murmur

Question 3

What murmur do you find in: aortic stenosis

Answer 3

systolic ejection click with crescendo-decrescendo (suprasternal thrill on palpation)

Question 4

What murmur do you find in: mitral regurgitation

Answer 4

holosystolic murmur @ apex (accentuated by clenching fists, squatting or during expiration)

Question 5

What murmur do you find in: aortic regurgitation

Answer 5

early blowing daistolic murmur (wide pulse pressure and bounding pulses)

Question 6

What murmur do you find in: mitral stenosis

Answer 6

opening snap followed by diastolic rumble

Question 7

What disease is associated with: VSD

Answer 7

fetal alcohol syndrome

Question 8

What disease is associated with: ASD

Answer 8

down syndrome (ostium primum)

Question 9

What disease is associated with: PDA

Answer 9

congential Rubella

Question 10

What disease is associated with: transposition of the great vessels

Answer 10

maternal diabetes

Question 11

What disease is associated with: Coarctation

Answer 11

turner syndrome (often seen with PDA)

Question 12

What disease is associated with: mitral valve stenosis

Answer 12

chronic rheumatic fever

Question 13

What disease is associated with: mitral regurgitatoin

Answer 13

acute rheumatic fever

Question 14

Occlusion of right coronary artery leads to what type of infarction

Answer 14

posterior wall, posterior septum, and papillary muscles of the LV (can lead to mitral regurg).
–can lead to a L–>R shunt

Question 15

Occlusion of the left anterior descending artery (LAD) leads to what type of infarction

Answer 15

anterior wall and anterior septum of the LV. Most commonly involved artery.
–can lead to a L–>R shunt

Question 16

Occlusion of the left circucmflex artery leads to what type of infarction

Answer 16

lateral wall of the LV (can lead to a cardiac tamponade)

Question 17

What disease is associated with: congenital heart block

Answer 17

SLE

Question 18

What disease is associated with: endocardial fibroelastosis

Answer 18

mumps (primary)

Question 19

Aschoff bodies found in

Answer 19

Rheumatic heart disease. Granulomatous lesions in myocardium

Question 20

Libman sacks endocarditis

Answer 20

SLE

Question 21

Valvular calcification without commissural fusion

Answer 21

(calcific) aotrtic stenosis (as opposed to aortic stenosis caused by rheumatic fever which as fusion of valvular fissures)

Question 22

Hyperthyroidism is associated with what type of HF?

Answer 22

High output HF (Thiamine def - beriberi - can look like hyperthyroidism)

Question 23

Homer-Wright rosettes

Answer 23

Wilms Tumor

Question 24

Adenosine deaminase def

Answer 24

Severe combined immunodef (also def in Il-2 can cause this)

Question 25

CD-40 ligand def

Answer 25

Hyper-Ig M (due to lack of class switching initiated by T-cells cell signal…def in t-cells although manifests as b-cell)