neoplasia (tumor markers, oncogenes, tumor suppressor genes) Flashcards
1
Q
alkaline phosphatase
A
mets to bone, liver, paget disease of bone, seminoma
2
Q
alpha fetoprotein
A
normally made by fetus; hepatocellular carcinoma; hepatoblastoma; yolk sace tumor; testicular cancer;
3
Q
b-HCG
A
hydatidiform mole and choricocarinomas; testicular cancer
4
Q
ca-19-9
A
pancreatic cancer
5
Q
ca-125
A
ovarian cancer
6
Q
calcitonin
A
medullary thryoid carcinoma
7
Q
CEA
A
nonsepcific but produced in 70% of colorectal and pancreatic cancers; also produced by gastric, breast, and medullary thryoid carcinomas
8
Q
s-100
A
neural crest origin: melanomas, neural tumors, schwannomas, langerhans cell histiocytosis
9
Q
TRAP
A
hairy cell leukemia (b-cell neoplasia)