Pathology Flashcards

1
Q

What are the 5 cardinal signs of inflammation?

A

Rubor, DOlor, calor tumour/swelling, functio laesa (loss of function)

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2
Q

What is the celllular response to injury?

A
  • margination
  • chemotaxis
  • pavementation
  • emigration
  • phagocytosis
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3
Q

What are the hemodynamic changes to injury?

A
  • vasoconstriction
  • vasodilation
  • increased vascular permeability
  • blood stasis
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4
Q

What are the types of acute inflammation?

A
  • abcess
  • ulcer
  • fistua
  • sinus
  • scar
  • keloid
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5
Q

What tissues are found with chronic inflammation?

A
  • epitherlioid, TB (granulomatous)
  • Langhan’s cells, TB
  • granulomatous change
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6
Q

What are the tissue changes seen with chronic inflammation?

A
  • metaplasia
  • dysplasia
  • anaplasia
  • neoplasia
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7
Q

Types of necrosis?

A
  • coagulative
  • liquefactive
  • caseous
  • enzymatic
  • fatyy
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8
Q

Types of degradation?

A
  • Zenker’s

- Wallerian

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9
Q

What is the progressional change of the nucleus when the cell is injured?

A
  • pyknosis
  • karyorrhexis
  • karyolysis
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10
Q

What are some immune deficiencies?

A
  • Bruton’s agammagloulinemia
  • DiGeorge Syndrome
  • Severe combined immune deficiency
  • Wiskott-Aldrich syndrome
  • Chediak-Higaski
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11
Q

What are some sex linked disorders?

A
  • Duchennes muscular dystrophy

- hemophilia

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12
Q

What are the autosomal chromosomal diseases?

A
  • Down’s syndrome
  • Klinefelter’s
  • Turner’s
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13
Q

What are the autosomal dominant diseases?

A
  • Marfans syndrome
  • Ehlers-Danlos syndrome
  • Osteogenesis imperfecta
  • Adult polycystic disease of kidney
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14
Q

What are the types of autosomal recessive disorders?

A
  • Glycogen storage
  • Lysosomal storage
  • Amino acid disorder
  • Metabolic
  • Hemopoietic
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15
Q

What are the glycogen storage autosomal recessive disorders?

A
  • Von Gierke
  • McArdle
  • Pompe
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16
Q

Lysosomal Storage Disorders?

A
  • Tay-Sachs
  • Gaucher (most common)
  • Niemann Pick
17
Q

Amino Acid Disorders?

A
  • Phenylketonuria

- Alkaptonuria

18
Q

Metabolic Disorders?

A

Cystic Fibrosis

19
Q

Hemopoietic disorders?

A
  • Sickle Cell Disease
  • Sickle Cell Trait
  • Thalassemia
20
Q

Recessive sex link disorders?

A
  • Duchenne Muscular Dystrophy
  • Becker’s Muscular Dystrophy
  • Hemophilia A/B
  • Lesch-Nyhan syndrome
21
Q

Dominant sex-linked disorder?

A
  • Vitamin D resistant rickets