pathology Flashcards
what are the types of atelectasis ?
1) resorption
2) compression
3) contraction (Cicatrization)
which type of atelectasis is not reversible ?
contraction
what are the histologic characteristics of ARDS ?
1) DAD (diffuse alveolar damage)
2) Hyaline membrane
3) fibrin rich edema which contains necrotic cells
4) proliferation of type 2 pneumocytes
5) intra alveolar fibrosis
6) thickening in the alveolar septa (due to collagen deposit)
*note: in the X-ray it will cause bilateral lung opacities
the characteristics of emphysema ?
1) enlargement of the air spaces
2) destruction of the alveolar walls +capillaries ( decrease in SA)
3) NO FIBROSIS
main cause is cigarette smoking
what type of emphysema is associated with chronic bronchitis ?
Centriacinar emphysema
note :it is more common and severe in the upper lobes (specifically the apex)
what type of emphysema is associated with a1- antitrypsin deficiency ?
panacinar emphysema
note: it is more common in the lower lobes
what is the most common cause of spontaneous pneumothorax ?
distal acinar emphysema
what is the most common form of emphysema ?
irregular emphysema
true or false
emphysema can lead to Cor pulmonale
true
how do we diagnose chronic bronchitis ?
persistent productive cough in 3 consecutive months for at least 2 consecutive years
true or false
chronic bronchitis with significant airway obstruction is almost always associated with emphysema
true
true or false
inflammation in chronic bronchitis contains eosinophils
false, it is without eosinophils
bronchiolitis obliterans is :
complete obliteration of the lumen because of fibrosis
histologic diagnosis of chronic bronchitis presents ?
1) enlargement of the mucus secreting glands
2) metaplasia of goblet cells
3) bronchial cell wall fibrosis
the most striking morphologic features in asthma are ?
1) curschmann spirals
2) eosinophils
3) charcot leyden crystals