pathology Flashcards

1
Q

what are the types of atelectasis ?

A

1) resorption
2) compression
3) contraction (Cicatrization)

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2
Q

which type of atelectasis is not reversible ?

A

contraction

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3
Q

what are the histologic characteristics of ARDS ?

A

1) DAD (diffuse alveolar damage)
2) Hyaline membrane
3) fibrin rich edema which contains necrotic cells
4) proliferation of type 2 pneumocytes
5) intra alveolar fibrosis
6) thickening in the alveolar septa (due to collagen deposit)

*note: in the X-ray it will cause bilateral lung opacities

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4
Q

the characteristics of emphysema ?

A

1) enlargement of the air spaces
2) destruction of the alveolar walls +capillaries ( decrease in SA)
3) NO FIBROSIS

main cause is cigarette smoking

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5
Q

what type of emphysema is associated with chronic bronchitis ?

A

Centriacinar emphysema

note :it is more common and severe in the upper lobes (specifically the apex)

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6
Q

what type of emphysema is associated with a1- antitrypsin deficiency ?

A

panacinar emphysema

note: it is more common in the lower lobes

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7
Q

what is the most common cause of spontaneous pneumothorax ?

A

distal acinar emphysema

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8
Q

what is the most common form of emphysema ?

A

irregular emphysema

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9
Q

true or false

emphysema can lead to Cor pulmonale

A

true

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10
Q

how do we diagnose chronic bronchitis ?

A

persistent productive cough in 3 consecutive months for at least 2 consecutive years

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11
Q

true or false

chronic bronchitis with significant airway obstruction is almost always associated with emphysema

A

true

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12
Q

true or false

inflammation in chronic bronchitis contains eosinophils

A

false, it is without eosinophils

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13
Q

bronchiolitis obliterans is :

A

complete obliteration of the lumen because of fibrosis

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14
Q

histologic diagnosis of chronic bronchitis presents ?

A

1) enlargement of the mucus secreting glands
2) metaplasia of goblet cells
3) bronchial cell wall fibrosis

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15
Q

the most striking morphologic features in asthma are ?

A

1) curschmann spirals
2) eosinophils
3) charcot leyden crystals

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16
Q

clinical features of asthma

A

1) dyspnea
2) cough
3) wheezing
4) chest tightness

17
Q

status arthmaticus causes?

A

1) hypercapnia
2) acidosis
3) hypoxia

note: it can be fatal ,it can last days or even weeks

18
Q

in advanced cases of restrictive pulmonary diseases, what is the appearance of the lung called

A

honeycomb appearance

19
Q

what is the difference between the LN in sarcoidosis and in tuberculosis ?

A

in sarcoidosis the LN are not matted , they are not adherent and they do not ulcerate .

20
Q

what is the other name for idiopathic pulmonary fibrosis ?

A

cryptogenic fibrosis alveolitis

21
Q

the most prevalent chronic occupational disease in the world is ?

A

silicosis

22
Q

which pneumoconiosis increase the risk of TB ?

A

silicosis

23
Q

does cessation of smoking decrease the risk of lung cancer ?

A

yes, but the risk never reaches the baseline