Pathology Flashcards
0
Q
Calcium soap formation
A
Saponification
1
Q
Mucoviscidosis
A
Cystic Fibrosis
2
Q
Not promptly destroyed necrotic cells reabsorbed and attract calcium salts and other minerals and become calcified
A
Dystrophic calcification
3
Q
Fragments of DNA in apoptotic cells
A
DNA ladders
4
Q
Large homogenous eosinophilic inclusions produced by distended ER secondary to excess production of normally secreted proteins
A
Russell bodies
5
Q
Immature B and T cells
A
Lymphoblasts
6
Q
Macrophage in burkitt lymphoma
A
Burkitt cells
7
Q
Treatment for ALL
A
Asparaginase
8
Q
CD 33, CD 34 positive
A
AML
9
Q
Aleukemic leukemia
A
AML
10
Q
Auer rods
A
APML > AML
11
Q
Leukemia with spontaneous mucosal and cutaneous bleeding
A
AML
12
Q
Leukemia with CNS involvment
A
ALL
13
Q
T(15;17)
A
APML
14
Q
Chloroma
A
Blast crisis of CML
15
Q
Dry tap on BMA
A
Hairy cell leukemia
16
Q
Ann Arbor Staging
A
Hodgkins lymphoma
17
Q
T(14;18)
A
Follicular lymphoma
18
Q
Cloverleaf cells
A
Adult t cell lymphoma
19
Q
Cd4 t cells in band like aggregates
A
Sezary lutner cells
20
Q
Russell bodies
A
Multiple myeloma
21
Q
Pseudo pelger huet cells
A
MDS
22
Q
Panmyelosis
A
Polycythemia vera
23
Q
In polycythemia, ESR will
A
Decrease
24
Skin blisters are ____ type of inflammation
Serous inflammation
26
Type of collagen deficient in achondrogenesis type II
Type II collagen
27
Phase of wound healing where there is already collagen deposition
Maturation phase
34
TGF-B is impt in synthesis of
Collagen
35
Heart failure cells are found in
Chronic pulmonary congestion
36
Nutmeg liver
Chronic Passive congestion (CPC)
37
Blood, CSF and brain tissue in volume equilibrium
Monro-kellie doctrine
38
Pathologic counterpart of hemostasis
Thrombosis
39
Arteriolar vasoconstriction is transiently augmented by secretion of
Endothelin
40
Antibodies in APAS
Anti-cardiolipin
| Lupus anticoagulant
41
Tigered effect is seen in
Fatty change (steatosis) in Heart
42
Distinguishes antemortem fibrosis from postmortem fibrosis
Lines of Zahn (lamination)
43
Difference of Postmortem Lividity from Postmortem Thrombosis
PL is in direct contact with surfaces
| PT is not attached to underlying wall
44
Thrombi on heart valves called
Vegetations
45
Endocarditis in SLE patients
Libman sacks endocarditis
46
Bacterium in MARANTIC ENDOCARDITIS
Streptococcus bovis
47
Cardiac tamponade will lead to what type of shock
Cardiogenic shock
48
Pulmonary embolism will lead to what type of shock
Cardiogenic shock
49
Heart failure cells are found in
Chronic pulmonary congestion
50
Nutmeg liver
Chronic Passive congestion (CPC)
51
Blood, CSF and brain tissue in volume equilibrium
Monro-kellie doctrine
52
Pathologic counterpart of hemostasis
Thrombosis
53
Arteriolar vasoconstriction is transiently augmented by secretion of
Endothelin
54
Antibody seen in limited form of scleroderma
Anti-centromere
55
Type of graft with best survival rate
Autograft
56
Acute cellular rejection causes endothelitis
| Acute humoral rejection causes what vascular injury
Necrotizing vasculitis
57
Treatment of Bruton's XLA
Pooled gamma globulin
58
C3 deficiency - recurrent infection due to what bacteria
S.aureus
59
Sago spleen or lardaceous spleen is seen in
Amyloidosis
60
Proto-oncogene: abl
CML
61
Proto-oncogene: c-myc
Burkitt lymphoma
62
Proto-oncogene: bcl-2
Follicular lymphoma
63
Proto-oncogene: Erb-b2
Breast CA
Ovarian CA
Gastric CA
64
Proto-oncogene: K-ras
Colon CA
65
Proto-oncogene: L-myc
Lung CA
66
N-myc
Neuroblastoma
67
Proto-oncogene: ret
MEN types II and III
68
Proto-oncogene: c-kit
GIST
69
Tumor suppressor gene: p16
Melanoma
70
Tumor suppressor gene: APC
Colorectal CA
71
Tumor suppressor gene: WT1
Wilms tumor
72
Tumor suppressor gene: DPC
Pancreatic CA
73
Tumor suppressor gene: DCC
Colon CA
74
Tumor suppressor gene: Rb
Retinoblastoma
| Osteosarcoma
75
Mendelian disorder
| Affected male parent with unaffected wife transfer gene to all his daughters but none of his sons
X-linked Dominant
76
Affected mother transfer genes to all offspring
Mitochondrial inheritance
77
Mutant gene present but phenotypicly normal
Incomplete penetrance
78
Mendelian d/o
Many generations affected
Age onset is delayed
Autosomal dominant
79
Mendelian d/o
Clinically presents at childhood
Seen in 1 generation only
Autosomal recessive
80
Affected male does not transmit gene to sons
| All daughters are carriers
X-linked recessive
81
Ectopia lentis is seen in
Marfan syndrome
82
Lysosomal accumulation of sphingomyelin
Niemann pick disease type a and b
83
Zebra bodies found in
Niemann pick disease
84
Distended phagocytic cells with crumpled tissue paper appearance
Gaucher cells
85
Intracytoplasmic glycogen accumulation in muscle only
McArdle's (type V)
86
Prototype trinucleotide repeat dse
Fragile x synd
87
Happy puppet syndrome is C/M in _____ syndrome
Angelman
88
Type of hypersensitivity leading to complement mediated cell lysis
Cytotoxic hps
| Type II
89
Autoantibody in SLE
ANA
| Anti-dsDNA
90
Autoantibody in drug induced lupus
Anti-histone
91
Autoantibody in mixed connective tissue dse
Anti-RNP
92
Autoantibody in CREST syndrome
Anti-centromere
93
Autoantibody in diffuse scleroderma
Anti-scl70
94
Autoantibody in sjogren syndrome
Anti-SS-A
95
Autoantibody in primary biliary cirrhosis
Anti-mitochondrial
96
Fragmented RBCs
Schistocytes
97
RBC with spikes
Burr cells/Echinocytes
98
Macro-ovalocyte RBCs are seen in
Megaloblastic anemia
99
Antibody causing Immune Thrombocytopenic Purpura
Anti-platelet antibody
100
Congestion of splenic sinusoids
Megakaryocytic hyperplasia in bone marrow
Megathrombocytes in peripheral blood
Immune thrombocytopenic purpura
101
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Fever
Thrombocytopenia
Microangiopathic hemolytic anemia
Neurologic deficits
Renal failure
```
Thrombotic thrombocytopenic purpura
102
Treatment for Von Willebrand Disease
Desmopressin
| Concentrates containing Factor VIII and vWF
103
Widespread microthrombi in placenta
Toxemia of pregnancy
104
Acute herpetic gingivostomatitis is caused by
HSV-1
105
Nests of round to oval chief cells surrounded by delicate vascular septae
Zellballen
| Paraganglioma
106
Dendritic cells in skin are called
Langerhans
107
First histologic change in progression of dysplastic nevus to melanoma
Lentiginous hyperplasia
108
Vertical growth phase of melanoma is heralded by appearance of a
Nodule
109
Dermatitis herpetiformis is associated with what intestinal disease
Celiac disease
110
Earliest histologic lesion in melanocytic nevus
Junctional nevi
111
Most common location of Paragangliomas
Carotid bodies
112
Components of OEIS complex
Omphalocoele
Extrophy (bladder)
Imperforate anus
Spina bifida
113
Rescue therapy for Doxorubicin
Dexrazoxane
114
Rescue therapy for Cisplatin
Amifostine
115
Dominant symptom and sometimes the only clinical manifestation of urothelial cancers
Painless hematuria
116
Fibromatosis of Buck's fascia causing penile curvature
Peyronie disease
117
Bell clapper deformity is seen in
Testicular torsion
118
Blood vessel invaded in Syphilitic aneurysm
Vasa vasorum of thoracic aorta
119
Pre existing histologic lesion of Aortic dissection
Cystic medial degeneration
