Pathology Flashcards
What is an important question to ask the patient before scanning the GB?
The last time they have had anything by mouth
Clinical symptoms of GB disease…
RUQ pain especially after fatty meals Nausea & vomiting Right shoulder & midepigastric pain Jaundice Chills & fever
What is sludge?
Concentrated bile - soft echoes layered in dependent part of GB that will change with patient position
Gravity dependent
Asymptomatic or with associated GB disease
What causes sludge?
Thickened bile Bile stasis (doesn't move) Prolonged fasting or hyper alimentation therapy (feeding tube)
What can resemble a mass or psuedo tumor when related to sludge?
Tumefactive sludge - use color Doppler - long standing biliary obstruction
Describe a sludge ball…
Medium level echogenic masses
What is the normal thickness of the GB wall?
Less than 3 mm
Where do you measure the thickness of the GB wall?
Anterior wall
What is Cholelithiasis?
GB stones; can be large or small
Tiny stones are dangerous because they can obstruct the bile flow in the ducts
Cholelithiasis etiology…
Abnormal bile composition
Stasis
Infection
Stages of gallstone formation…
Saturation of bile
Nucleation (forming a blob)
Growth
Gallstone composition…
Cholesterol
Calcium bilirubinate
Calcium carbonate
What is the most common GB disease?
Cholelithiasis
Cholelithiasis clinically…list the “F’s”
Fat Female Forty Fertile Fair Flatulent
Causes of Cholelithiasis…
Obesity Diabetes Pregnancy Oral contraceptives Estrogen replacement Pancreatitis Biliary infection Alcohol cirrhosis Diet induced Rapid weight loss program Feeding tube
What % of Cholelithiasis evokes no clinical manifestations?
80%
What is a serious consequence in obstruction of the cystic duct or CBD?
GB hydrops - getting bigger from fluid build up
What is Bouveret?
Gastric outlet obstruction caused by gallstone in the pylorus or proximal duodenum
Cholelithiasis sonographically…
Gallstones Increased GB size Decubitus Acoustic shadowing Acoustic impedance of gallstones WES sign
What is the WES sign?
Completely filled with gallstones
No lumen…all shadow
Wall Echogenic Shadowing
When will you see floating gallstones?
Prolonged fasting, air, oral cholecystogram
What do you need to make sure your not confusing for gallstones?
GB valves
What is cholecystitis?
Inflammation of the GB
What are the 5 forms of cholecystitis?
Acute Chronic Acalculous Emphysematous Gangrenous
What is a Murphy’s sign?
A hypersensitivity with deep palpitation in the sub costal area when a patient takes in a deep breath that may produce inspiratory arrest
Describe acute cholecystitis…
Cholelithiasis Cystic duct obstruction or neck of GB obstruction (Hartmann's Pouch) Females \+ Murphy's Fever Leukocytosis Abn LFTs Pancreatic reflux
The most common cause of acute cholecystitis is ___________.
Gallstones - impacted & extrinsic pressure
Acute cholecystitis sonographically…
Thickened wall
Edema-halo
Enlarged (greater than 5 cm trans)
Pericholecystic fluid
Describe chronic cholecystitis…
Contraction of GB
Coarse wall thickening
WES sign
What is the most common form of GB inflammation?
Chronic cholecystitis
Clinical symptoms for cholecystitis…
Intermittent RUQ pain
Intolerance to fatty, fried food
Intermittent nausea and vomiting
Acute inflammation of the GB is ___________.
Acalculous cholecystitis
Acalculous cholecystitis is absent of ___________.
Gallstones - Cholelithiasis
Clinical workup of acalculous cholecystitis…
+ Murphy’s
Abn LFTs
Increased amylase
Increased WBC
Acalculous cholecystitis sonographically…
Decreased blood flow in the cystic artery
Extrinsic compression of the cystic duct by a mass
GB wall thickened
Sludge
Pericholecystic fluid
Describe emphysematous cholecystitis…
Acute cholecystitis
Gas forming bacteria in wall and lumen into ducts
Relationship to diabetes
May lead to gangrene with associated perforation
Surgical emergency
Fever, pain, infection