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Medicine > Pathology > Flashcards

Pathology Flashcards

1
Q

Intestinal Metaplasia in GE junction

A

Esophageal squamous —> intestinal columbar

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2
Q

Earliest manifestation of reversible injury on cells

A

Cellular swelling

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3
Q

Hallmark of chronic hepatitis

A

Bridging fibrosis

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4
Q

Pathophy of cachexia, suppresses appetite center & promotes beta oxidation of FA for fuel

A

Elevated TNF-a

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5
Q

Trea-bark apperance of ascending aorta

A

Tertiary syphilis

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6
Q

Nuclear
Fragmentation
Shrinkage
Fading

A

Karyorrhexis
Pyknosis
Karyolysis

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7
Q

Onion skinning
Fibrinoid necrosis

A

Malignant HTN

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8
Q

Caseous necrosis

A

TB
Granuloma formation / epithelioid histiocytes —> Langhan giant cells / horseshoe pattern

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9
Q

Defect in Progeria

A

Progeria - premature aging
Defect gene for DNA helicase

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10
Q

Thyroid CA buzz

Psammoma
Orphan Annie

A

Papillary Thyroid CA

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11
Q

Thyroid CA buzz

Vascular invasion / Hurthle Cell

A

Follicular Thyroid CA

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12
Q

Thyroid CA buzz

Amyloid deposuts / C-cell hyperplasia

A

Medullary Thyroid CA

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13
Q

Conditions where you see psammoma

A

Papillary Thyroid Ca
Serous Cystadenoma
Meningioma
Mesothelioma

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14
Q

Apoptosis: Execution caspase

A

Caspase 3 & 6

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15
Q

Apoptosis: Extrinsic Caspase

A

Caspase 8 9 10
(10 - humans)

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16
Q

Hallmark of Acute Inflammation

A

Increased vascular permeability

17
Q

Red clots VS white clots

A

Red clots - RBCs & fibrin
White clots - platelets & fibrin

18
Q

Dose for alteplase

A

0.9 mg/kg, max dose of 90mg over 1hr with initial 10% of dose given over 1 min

19
Q

Major complications of rTPA treatment

A

Symptomatic intracerebral hemorrhage
Angioedema

20
Q

Dose of anti-TB drugs in adults & children

A

HRZE
Adults: 5/10/25/15 mg/kg
Children: 10/15/30/20 mg/kg

21
Q

Pulseless disease

A

Takayasu arteritis

22
Q

Schiller Duval bodies

A

Yolk sac tumor

23
Q

Marfan syndrome lens sublaxation

A

Outward, Upward

Medicine (9 decks)

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