PATHOLOGY

Question 1

Which INTERLEUKIN is anti- inflammatory cytokine?

Answer 1

IL - 10

Question 2

Inclusion body seen in Rabis?

Answer 2

Negri bodies

These are eosinophillic, sharply outlined, pathognomic inclusion bodies found in CYTOPLASM OF NERVE CELLS containing the Rabis virus

Question 3

Markers for MALIGNANT MELANOMA..

Answer 3

1. HMB-45
2. S-100
3. Melan - A

Question 4

Type of filament in the Mallory Hyalin body…

Answer 4

Present in alcoholic liver disease

INTERMEDIATE FILAMENT

Question 5

Mallory hyaline bodies

Answer 5

Intracellular Hyaline depositions
( New Indian WATCH)

_NASH
_Indian childhood cirrhosis
_Wilson
_Alcoholic liver
_Tumors of HCC
_Cirrhosis like Primary Biliary Cirrhosis
_Hyperplasia ( focal nodular)

⭐composition
- Intermediate filaments ( CK 8 & 18 )

Question 6

Psammoa bodies

Answer 6

Foci of Dystrophic Calcification

_Papillary CA Thyroid
_Papillary CA RCC
_Meningioma
_Prolactinoma
_Serous Cystadenocarcinoma Ovary

Question 7

Telltale sign of free radical injury

Answer 7

Aging pigments
Or
Wear and tear pigments
⬇️
Brown atrophy of Liver and Heart
(Perinuclear brown pigment)

Question 8

CD 95

Answer 8

FAS protein
_ of Extrinsic Pathway

⭐FLIP protein
_ inhibitor of Extrinsic pathway

Question 9

Most common Cytokine in Cancer Cachexia…

Answer 9

TNF alpha

Question 10

Malignancy which do not metastasize

Answer 10

1. BCC
2. Glioma

Question 11

Bread n Butter pericarditis

Answer 11

Fibrinous exudate in Pericardiac space

_ seen in ⭐Reumatic carditis

Question 12

Activated protein C inhibit Clotting mechanism by

Answer 12

Inhibiting
1. Factor 5a
2. Factor 8a

Question 13

Autosomal Dominant

Answer 13

⭐He Has A Very DOMINANT Father

H- Huntington
H- Hereditary spherocytosis
A- Achondroplasia
V- VWD, VHL
D- Dystrophia myotonia
O- Osteogenesis imperfecta
M- Marfan syndrome
I- Intermittent porphyria
N- NF-1
A- Adult onset polycystic kidney disease
N- NF-2
T- Tuberous sclerosis
F- Familial adenomatous polyposis
Familial hypercholestrolemia

Question 14

HLA matching not done in

Answer 14

1. Liver
2. Heart
3. Lungs
4. Cornea transplant