Pathologies Related to the Low Back #3 Flashcards
What is nephrolithiasis?
Kidney stones or renal calculi
What makes up the urinary system?
Structure: kidneys, ureters, bladder, and urethra
What is the urinary system function?
- Filter fluid from renal blood flow
- Remove waste
- Retain essential substances for electrolytes and ph
- Stimulates RBC production
- Blood pressure regulation
- Converts Vitamin D (absorbs Ca2+) to its active form
What is the etiology and risk factors for nephrolithiasis?
- Disorders that lead to hyperexcretion of Ca2+ and uric acid i.e. Hyperthyroidism
- NOT primarily drinking water
- Obesity
- High animal protein intake
What is the incidence/ prevalence of nephrolithiasis?
3rd MOST common urinary tract disorder behind
infections and prostate conditions
What is the pathogenesis of nephrolithiasis?
Hard mass of salts composed of Ca2+ > uric acid and other minerals deposited in urinary system
What signs and symptoms might you see with nephrolithiasis?
- Referred P! into T10-L1 dermatomes
- May begin with intermittent unilateral LBP
- Progress to acute/severe back and flank (between ribs and iliac crests) and possibly abdominal P!
- Radiating P! to the groin and perianal regions
- Bladder dysfunction
- Eventually unrelenting P!
- N&V due to P! severity
- Infection (kidney or urinary tract) could occur so infection S&S may be present
What might you find with percussion and palpation with nephrolithiasis?
- Murphy percussion test over kidney determines referral
- One firm and closed fisted percussion over 12th costovertebral angle
- WNL = painless
- P! also may be present with bladder palpation/percussion
What kind of referral is nephrolithiasis?
Urgent but possibly emergent referral depending on pain severity
Is the skeleton metabolically active?
Yes
The skeleton undergoes continuous remodeling throughout life with an _____ turnover of bone.
Annual
Remodeling of the skeleton is necessary to?
- Maintain the structural integrity of the skeleton
- Serve metabolic demands as a storehouse of Ca2+ and phosphorus
Bone mass peaks between what ages?
25-35 yrs
What is osteoporosis?
Persistent, progressive metabolic disease characterized by:
- Low bone mass
- Impaired bone quality
- Decreased bone strength
- Enhanced risk of fractures
What are the two types of osteoporosis?
- Primary: MOST common and associated with aging
- Secondary: consequence of disease or medication
What is the incidence level/ prevalence of osteoporosis?
- Not often a presenting diagnosis
- 70% undiagnosed; found during investigation of
other conditions - Increasing number in younger individuals
- Expected to increase with aging population
- Highest in post-menopausal biological women with
estrogen deficit and Scandinavian ancestry - 33% of biological women and 20% of biological men
over 50 yrs. will suffer an osteoporotic fx
What is the most common metabolic bone disease?
Osteoporosis
What is a precursor to Osteoporosis?
Osteopenia or low bone mass
What are risk factors of osteoporosis?
- Lower Estrogen
- Genetics
- Social habits: > 2 beers, > 1 glass of wine, > 1 liquor shot or > 3 cups (8 oz. in a cup) of caffeine per day
Lower estrogen levels causes what?
- Limits release of Ca2+ into blood and absorption
- Associated with menopause and abnormal menses
Lower testosterone levels cause what?
Lower testosterone also limits release of Ca2+ into blood