Pathologies Related to the Low Back #2 Flashcards
What is ankylosing spondylitis?
A type of spondyloarthropathy OR spondyloarthritide
What is the etiology of ankylosing spondylitis?
- Genetics: 90% are positive for HLA-B27 antigen on a blood test
- Environmental
What is the incidence level/ prevalence of ankylosing spondylitis?
- Almost as common as RA
- Onset < 40 and typically between 15-30 yrs.
- Biological males 2-3x > females
- MOST common in lumbosacral region
What is the pathogenesis of of ankylosing spondylitis?
- Chronic inflammation at cartilage, tendon, ligament, and synovium attachments to bone
(entheses) - Erosive bony overgrowth and osteopenia (weakened bone)
- Leads to fusion of involved joints
What does ankylosing spondylitis look like on an x-ray?
Shows up as a bamboo appearance
What are common signs and symptoms of ankylosing spondylitis?
- Autoimmune S&S
- Multi-jt. inflammation and P!
- Familial predisposition
- Extraarticular involvement of eyes, skin, GI tract, and renal and cardiac systems
What condition do some describe as “hurts to see, pee, and bend my knee”
Ankylosing Spondylitis
What might you see in terms of multiple joint inflammation and P! when it comes to ankylosing spondylitis?
- > 30 min. of P!/stiffness after prolonged positions
- Improved P! with easy and regular movement
- Chronic inflammation and P! of axial skeleton MOST often
- Asymmetric or unilateral extremity involvement to a lesser degree
- Typically, of smaller extremity joints but can affect larger ones
- Localized to entheses or insertions of ligaments, tendons, and fascia- so numerous – itis’
What kind of history might someone with ankylosing spondylitis present with?
- Progressive LBP primarily from greatest influence on sacroiliac (SI) jts. > neck and lumbar regions
- Onset < 40 yrs.
- Insidious lasting > 3 mths.
- No change with rest
- Night pain from static positioning
- Buttock and hip P!
What observations will you see with ankylosing spondylitis?
- Hyperkyphosis
- Loss of lumbar lordosis
What might you see in your scan and biomechanical exam for someone who has ankylosing spondylitis?
- Multiple directions of limited ROM/accessory motion of involved joints… possibly fused
- Combined motion: multiple consistent block
- Limited thorax excursion with manubrial and rib springs, possibly compromising cardiopulmonary function
- Positive Berlin and Inflammatory Back Pain CPRs
What kind of referral is ankylosing spondylitis?
- Urgent referral to rheumatologist
- A “Do Not Want To Miss” condition in any young adult with low back pain
What does the berlin criteria tell us?
Berlin Criteria: ≥2
- (+) likelihood ratio of 2.2-3.8 or 88% probability
- 70% sensitive
1. AM stiffness
2. P! with rest AND relief with exercise
3. Awakening with LBP during 2nd half of night
4. Alternating buttock P!
What does the IBP criteria tell us?
IBP Criteria (≥ 4 = 80% sensitive / 72% specific)
1. < 40 yrs. of age
2. Gradual onset
3. Relief with exercise
4. No change with rest
5. Night P! with improvement getting up
What kind of PT Rx is possible for ankylosing spondylitis?
- Be sensitive to trauma in patients with an AS diagnosis
- Fall prevention
- Gentle ROM, manual therapy, and MET considering fragility
- Postural education
- All the above would also help with bone pathologies like Osteoporosis and Osteomalacia that will be discussed later
What kind of complications might occur with ankylosing spondylitis?
- Osteoporosis
- Fractures
- Craniovertebral subluxations
- Stenosis
- Fusion in an upright or MORE often forward bent position
- Cardiopulmonary disorders
What is prostate cancer?
Cancer of the prostate which is a reproductive gland below the bladder that aids sperm function
What is the etiology of prostate cancer?
Unknown