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Microbiology > Pathogens Respiratory Transmission > Flashcards

Pathogens Respiratory Transmission Flashcards

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Biology 101 flashcards
1
Q

What is the gold std to test for TB?

A

Culture it

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2
Q

What is unique to Mycobacteria cell walls?

A

Mycolic acid, cord factor, wax D, Lipoarabinomannan

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3
Q

What is mycolic acid?

A

Basically a wax; makes mycobacteria difficult to kill; prevents lysozyme attack

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4
Q

What is cord factor?

A

It is toxic to mammals

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5
Q

What is Wax D?

A

An antigenic portion of the OM of mycobacteria

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6
Q

What is Lipoarabinomannan

A

Stimulates cytokine production in mammalian hosts

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7
Q

Presentation of Mycobacterium tuberculosis

A

Fatigue, fever, wt. loss, blood tinged sputum

Chronic cough that damages lungs

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8
Q

What is a granuloma?

A

Ball of immune cells that results from macrophages recruiting cells w/ cytokines. Trying to contain the infection/Isolate it

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9
Q

What is the pathogenicity of Mycobacterium Tuberculosis?

A

Spread Respiratory Droplets; prevent phagolysosome fusion; cord factor is cytotoxic; cytokine mediated inflammation b/c body trying to kill, but bact. won’t die

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10
Q

What causes leprosy?

A

Mycobacterium Leprae

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11
Q

What are the 2 types of Leprosy?

A

Tuberculoid - macular lesions, unilat. n. involvement

Lepromatous - progressive nodular lesions, bilat. n. death, bone respiration, extremity loss

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12
Q

How do you treat leprosy?

A

Sulfone and rifampin. Reduces sulfone resistance

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13
Q

What is the most common nosocomial infect. in AIDs pts?

A

Mycobacterium avium-intracellulare

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14
Q

What looks like a “fried egg” on the Cx?

A

Mycoplasma Pneumoniae

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15
Q

What is the difference b/w Mycobacteria and Mycoplasma?

A

The bact. has a unique cell wall, and the mycoplasma has no cell wall and only membranes

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16
Q

How does Mycoplasma pneumonia present?

A

Walking pneumonia or tracheobronchitis

17
Q

Epidemiology of M. pneumonia

A

Transmitted via resp. droplet; common in school-age children; more common in winter

18
Q

What is the main pathogenic factor in M. pneumonia?

A

Proline-rich adhesion protein that adheres to cells and is cytotoxic. NO INVASION of cells

19
Q

What Mycoplasma produces urease?

A

Ureaplasma Urealyticum

20
Q

What presents w/ Bilateral cervical lymph node enlargement and pseudomembrane formation in the back of the throat?

A

Corynebacterium diptheriae

21
Q

How is the Corynebacterium diphtheriae toxin obtained

A

beta-phage conversion

22
Q

What does the A part of Corynebacterium diphtheriae toxin do?

A

Binds to EGF-like receptor and is internalized

23
Q

What does the B part of Corynebacterium diphtheriae toxin do?

A

Binds NAD and ADP-ribosylates EF-2 stopping prot. synthesis

Microbiology (6 decks)

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