Patho Exam 6 Flashcards
Generalized seizure: Absence seizures
occurs in children, staring spells that last a few seconds
Causes of seizures
unknown
cerebral trauma
cerebral lesions
metabolic/nutritional disorders
decorticate response
mummy pose
flexion of arms, wrists, and fingers with adduction in upper extremities
neurogenic shock
form os distributive shock caused by the loss of the brainstem and higher center control of the sympathetic nervous system. Causes hypotension due to vasodilation.
serotonin
mood neurotransmitter
mood, appetite, social behavior, sexual drive, sleep, reminiscence, learning, and GI mobility
ACh
learning neurotransmitter
recollection, concentration, attention, muscular activities, thinking, and mood
cause of seizures in infants
infection and exposure to toxins in utero
Alzheimer’s pathology and risk factors
unknown cause
early neuronal degeneration in the hippocampus
followed by degeneration of neurons in cerebral cortex
intracellular neurofibrillary tangles
extracellular amyloid and tau plaques
risk factors related to age and family history
Parkinson’s etiology
Common onset age in 70s
More common in men
treatment of
ischemic stroke
hemorrhagic stroke
IS: minimizing infarct size and preserving neurologic function
HS: BP management, ICP monitoring and management
cause of seizures in elderly
stroke, Alzheimer’s, and tumors
classic symptoms of an acute subdural
headache, drowsiness, restlessness, agitation, and confusion
Receptive aphasia: transcortical motor/sensory
motor=nonfluent
sensory=fluent
loss of parasympathetic control
bradycardia and loss of the cardiac accelerator reflex
Receptive aphasia: word deafness
hears noise instead of words
generalized seizure
entire brain surface involved, including the thalamus and RAS. Loss of consciousness
main neurotransmitter for the PNS
ACh
prodoma
early sign of seizure. Headache, malaise, depression. May occur hours to days before seizure
treatment for meningococcal
rifampin
Cause of seizures in neonates
infection, congenital defect, premature
Epidural bleed
An artery is the source
Only 1-2% of bleeds
90% have skull fracture
temporal fossa
middle meningeal artery
can result in uncal herniation
coup (focal) injury
contra coup (polar) injury
coup is impact with surface
contracoup is the brain rebounding against the skull
Generalized seizure: tonic-clonic
jerking of many muscles
Receptive dysphasia: sensory/wernicke’s
trouble understanding what has been said to them
supratentorial vs infratentorial herniation
supra-brain tissue moves through tentorial notch
infra- tissue moves through the foramen magnum
What causes secondary ischemia?
edema
Generalized seizure: myoclonic
single or several jerks
Clinical manifestations of increasing ICP
headache, vomiting, altered level of consciousness, blurry vision, edema of optic disk, reduced pupillary response.
partial seizure: simple
no visible change
reperfusion injury
oxygen reenters cell after ischemia and produces reactive oxygen product similar to free radicals. Cell membranes undergo lipid peroxidation with formation of arachidonic acid which creates more free radicals.