PATHO Cellular Response, Inflammation

Question 1

Types of abnormalities with glucose or glycogen metabolism

Answer 1

I-Von gierke
II-pompe
III-Cori
V-Mc Ariel

Question 2

Anti apoptosis proteins

Answer 2

Bak
Bax
*Bcl2
Bakxstabbers

Good-bcl2 & bcl x

Question 3

Characteristics of Necrosis

Answer 3

NECLIP
N-nuclear changes
E-Enlarged
C-cell membrane disrupted
L-leaking enzymes
I-inflammation (of adjacent structures)
P-pathological

Question 4

APOPTOSIS characteristics

Answer 4

aPOPtosis--PIFS
Physiologic
Intact CM and contents
Fragments
Small

Question 5

Diseases associated with PSAMMOMA bodies (P S M M)

Answer 5

Papillary thyroid CA, Prolactinoma
Serous cystadenoCA of ovaries
Meningioma
Mesothelioma

Question 6

Major source of histamine

Answer 6

Mast cells

Question 7

Condition involving a genetic defect in phagolysosome formation

Answer 7

Chedak-Higashi syndrome

Question 8

Leukocyte Adhesion deficiency type I involves defective synthesis of what?

Answer 8

B2 integrins (LFA1 & Mac-1)

Question 9

Type II leukocyte adhesion deficiency

Answer 9

Loss of sialyl-Lewis X (ligand for E and P-selectin)

Question 10

Substances with anti inflammatory effects

Answer 10

Lipoxins
TGF-B (transforming growth factor)
IL-10
Resolvins
Protectins

Question 11

Substances with pro inflammatory effects

Answer 11

leukotrienes
Histamine
Serotonin