Patho Flashcards
Oncogene. Burkitt’s lymphoma
c-myc
Oncogene. CML
abl
Oncogene. Follicular and undofferentiated lymphomas
bcl-2
Oncogene. Breast, ovarian andd gastric carcinomas
erb-B2
Oncogene. Colon carcinoma
ras
Oncogene. Lung tumors
L-myc
Oncogene. Neuroblastoma
N-myc
Oncogene. Multiple Endocrine Neoplasia types IIA and IIB
ret
Oncogene. Gastrointestinal stromal tumor
c-kit
Tumor supressor gene. Retinoblastoma, osteosarcoma
Rb
Blocks G1 to S phase of cell cycle
Tumor supressor gene. Most human cancers, Li-Fraumeni syndrome
p53
Blocks G1 to S phase of cell cycle
Tumor supressor gene. Breast and ovarian cancer
BRCA1
Tumor supressor gene. Breast cancer
BRCA2
Tumor supressor gene. Melanoma
p16
Tumor supressor gene. Colorectal cancer
APC