Patho Flashcards

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0
Q

Oncogene. Burkitt’s lymphoma

A

c-myc

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1
Q

Oncogene. CML

A

abl

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2
Q

Oncogene. Follicular and undofferentiated lymphomas

A

bcl-2

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3
Q

Oncogene. Breast, ovarian andd gastric carcinomas

A

erb-B2

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4
Q

Oncogene. Colon carcinoma

A

ras

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5
Q

Oncogene. Lung tumors

A

L-myc

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6
Q

Oncogene. Neuroblastoma

A

N-myc

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7
Q

Oncogene. Multiple Endocrine Neoplasia types IIA and IIB

A

ret

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8
Q

Oncogene. Gastrointestinal stromal tumor

A

c-kit

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9
Q

Tumor supressor gene. Retinoblastoma, osteosarcoma

A

Rb

Blocks G1 to S phase of cell cycle

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10
Q

Tumor supressor gene. Most human cancers, Li-Fraumeni syndrome

A

p53

Blocks G1 to S phase of cell cycle

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11
Q

Tumor supressor gene. Breast and ovarian cancer

A

BRCA1

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12
Q

Tumor supressor gene. Breast cancer

A

BRCA2

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13
Q

Tumor supressor gene. Melanoma

A

p16

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14
Q

Tumor supressor gene. Colorectal cancer

A

APC

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15
Q

Tumor supressor gene. Wilm’s Tumor

A

WT1

16
Q

Tumor supressor gene. Pancreatic cancer

A

DPC

“Deleted in Pancreatic Cancer”

17
Q

Tumor supressor gene. Colon cancer

A

DCC. “Deleted on Colon Cancer”

18
Q

Tumor Marker. BPH, prostatitis

A

PSA

Prostate specific antigen

19
Q

Tumor Marker. Prostate carcinoma

A

Prostatic acid phosphatase

20
Q

Tumor Marker. Melanoma, neural tumors, astrocytes

A

S-100

21
Q

Tumor Marker. Metastases to bone, Paget’s Disease of Bone

A

Alkaline Phosphatase

22
Q

Tumor Marker. Neuroblastoma, lung and gastric cancer

A

Bombesin

23
Q

Tumor Marker. Hairy cell leukemia and B cell neoplasm

A

TRAP

Tartrate resistant acid phosphatase

“Trap the Hairy Animal”

24
Q

Tumor Marker. Pancreatic adenocarcinoma

A

Ca19-9

25
Q

Tumor Marker. Thyroid medullary carcinoma

A

Calcitonin